Asclepias Gigantea, Linn. (Mudar, Hind.) Nat. Ord. Asclepiadeae. Linn. Syst. Pentandria Digynia. Hab. India generally, and the Tenasserim Provinces.

Med. Prop. and Action. The root, bark, and juice of this tree have, for many centuries, been held in high esteem by the natives of India as em purgative, and diaphoretic. Dr. O'shaughnessy,i after extensive trials, found the alcoholic extract a powerful cathartic, but so uncertain in its operation that no reliance was to be placed upon it. Of the powdered bark of the root, however, he has formed a high estimate. In doses of gr. xxx. - gr. lx. it proves emetic alter an interval varying from twenty to sixty minutes, generally causing much nausea, and in about one case in every three, inducing a cathartic operation. In doses from gr. ij. - v. every half-hour, it proves nauseant, diaphoretic, and, after several doses, gently cathartic. On the whole, he considers it an excellent substitute for Ipecacuanha, for which it is substituted in Beng. Ph. in the preparation of Dover's Powder, thus: - Powdered Bark of rout of Mudar 3ij-, Opium 3j, Sulphate of Potash j., M. Its activity I depends upon an extractive principle, Mudarine.

* Gaz. des Hopitaux, 1855.

Printed Memo, forwarded by the Madras Medical Board, June, 1850. bengal Dispensatory, p. 453.

Dose of Powdered Hark of Root: as an emetic, gr. xxx. - gr. lx.; as a nau-seant and diaphoretic, gr. ij. - gr. v.

631. Therapeutic Uses

In Leprosy and Elephantiasis GrAeco-rvm, Mudar has long been a popular Indian remedy. Its real value was first investigated by Mr. Playfair, and subsequently by Mr. Robinson; they both agree in speaking highly of its efficacy, and state that, in the early stage of Leprosy, before the eruption becomes pustular, there is no medicine from which more benefit is to be derived than from this. Prof. Royle employed a closely-allied species, C. Hamiltonii, which is very common in Upper India, and known by the same native name. He states that he prescribed the fresh bark of the root, dried and powdered, alone, and successfully, in incipient cases of Leprosy and other cutaneous affections. It is inadmissible when the eruption is pustular. Dose, gr. iij. - x. thrice daily; but this quantity should be diminished if it produce much nausea or vomiting.

632. In Secondary Syphilis, Mr

Robinson§ regards Mudar as a highly valuable remedy. Where Mercury has been extensively employed, Mudar rapidly recruits the constitution, heals the ulcers, removes blotches from the skin, and perfects the cure.