1620. In Ascites, Iodine Proves Occasionally Serviceable; But, Observes Dr

Thompson,|| it does not act beneficially when the abdomen is tense; but after tapping, and reducing the excitement by antiphlogistics, it completely removes the serum. Mr. Copeman* states that he has derived great benefit from the following mixture: -1620 In Ascites Iodine Proves Occasionally Service 147 Iodinii j., Iod. Potas. ij., Aq. fvij., M. Of this, the dose for adults is ex.. - xv. - xxv.; and for children, ev. - x., thrice daily. In a case of Ascites in a girl aged eighteen, M. Leriche,t of Lyons, after the operation of paracentesis, injected the foliowing mixture into the peritoneal cavity: -T. Iodinii f j., Potas. Iod. 3j., Aq. fviij., M. Four ounces only of this injection were returned; the remainder was left in the abdomen. Some irritation followed, but the girl was discharged cured, nineteen days after the operation. M. Dieu-lafoy also relates two cases cured by Iodine injections. No ill effects resulted in either instance. Other examples are recorded by Dr. Costes. § (See also Potassii Iodidum.) The following rules for using Iodine injections in Ascites are given by Tessier:|| - 1. Do not empty the peritoneal cavity before vising the injection. Fatal peritonitis has followed a neglect of this rule. 2. The strength of the injection is to be in conformity with the composition of the peritoneal fluid, the strength being in direct relation to its alkalinity and albuminosity. 3. Practise a preliminary tapping some days previously if the abdomen is very voluminous, in order to diminish the peritoneal surface and so lessen the risk of peritonitis.

* Lib. of Med., vol iv. p. 198. Clin. Lect., vol. ii. p. 363. Med. Times and Gazette, March 5. 1864.

§ Tropical Climates, &c, op. cit., p. 229.

|| Dispensatory, p. 496.

1621. Other Diseases

In Inflammation of the Joints, the external use of Iodine is strongly advocated by Dr. Davies.¶ who considers it superior to the usual modes of treatment. He employs a tincture (ij., Alcohol fj.); but at the commencement of treatment this should be diluted to about half its strength or more. The Tincture diluted, he states, may be applied at once, all over the inflamed joint, with perfect confidence, not only that no mischief, but that good will be the result. But when the disease has been pretty well advanced, and where the swelling has been considerable, he prefers leeching the joint first, and then, a few hours after the bleeding has ceased, to apply the Tincture. It should be applied every day, for two or three times; then, every other or every third day, according to circumstances. If the part should acquire an increase of temperature, he prefers to lay over the joint a rag soaked in a spirit lotion; but this need not interfere with the use of Iodine. No lead or zinc lotion, or one medicated in any way, should be employed. (Davies.)

1622. In Hydrarthrosis, Iodine injections have been successfully employed by Velpeau and others. M. Bonnet* advises a mixture of 1 part of Iodine, 2 of Iodide of Potassium, and 8 of Water. He directs the quantity injected to be very nearly the same as that of the fluid drawn off. The puncture should be as small as possible, care being taken that air does not enter the joint. It is not necessary that the whole of the effused liquor should be allowed to escape. Inflammation generally ensues, but this subsides in a few days. The best position for making the puncture is immediately above the patella, the leg being fully extended at the time. Applied externally in strong solution, it often materially assists in causing absorption of the effused fluid. Five cases of Hydrarthrosis of the Knee-joint, successfully treated by Iodine injections, are related by Dr. Macdonnell. of Montreal.

* Med. Gaz., April 8, 1842.

Med. Times, vol. xvi. (1847), p. 275.

i Bull, de l'Acad. Roy. de Med., June 1844.

§ Gaz. Med de Paris, Oct. 29, 1853.

|| Ibid., April 22, 1854. ¶ Selections in Pathology, &c, p. 108.