547. In Hypochondriasis Attended With Gastric Irritation, Dr

Prichard § regards the Nitrate as almost the sole, or at any rate the best remedy, the bowels being at the same time properly regulated, and exercise taken.

548. In Ulceration Of The Stomach, The Nitrate, In Doses Of Gr

v. three or four times a day, seems in many instances highly useful. It appears to favour cicatrization at the same time that it restores the normal and healthy condition of the mucous membrane of the stomach.

549. In Diarrhaea Attended With Debility, Or Accompanying Phthisis, Dr

Theophilus Thompson || found this salt most efficacious. In 21 cases of which he kept notes, the Diarrhoea was entirely removed in 15, transient benefit resulted in 4, and in 2 only it failed to afford relief. The dose employed was gr. v., three or four times a day.

550. In Sub-acute and Chronic Dysentery, the Nitrate of Bismuth is spoken of in high terms by MM. Recamier and Trousseau.¶ After premising blood-letting, and other evacuants, they found it operate most beneficially as a sedative and astringent. It might be advantageously combined with Dovers' Powder.

551. In Chronic Laryngitis, Mm

Trousseau and Belloc speak highly of the efficacy of the local application of the Nitrate, by means of insufflation (see that article, part ii.). Dr. Williams ** states that, thus applied, he has seen it used with safety and advantage, in the worst forms of Chronic Laryngitis, even in that accompanying Phthisis. Its use, however, in the manner here advised, is far from being unobjectionable.

552. In Epilepsy, Dr

Copland states that he has tried this salt in two or three cases, both alone and with other tonics and anti-spasmodics, the bowels having been kept freely open, and that it has appeared to be quite as beneficial as the preparations of Zinc.

* Op. cit, p. 208.

Lond. .Journ. of Med., Aug. 1851. Memoirs of Lond. Med. Society, vol. v. § Cyc. Pract. Med., vol. ii. p. 557.

II Med. Chir Trans., vol. xiii. 1S48. ¶ Gazette Medicate, Feb. 26, 18(3. ** Lib. of Medicine. vol. iii. p. 50. Dict. Pract. Med., vol. i. p. 807.

553. In Ringworm, Dr

Dick, in his treatise on Porrigo, recommends an ointment of the Nitrate of Bismuth (3j. ad j.) to be rubbed into the diseased parts, night and morning, after washing. (E. Wilson.*)

554. In ulceration of the Septum Nasi, and also as a local application in Chronic Skin diseases, Dr. Pereira states that he has used the ointment {ante) with advantage. Bismuth may also be applied locally as a sedative and astringent, mixed with Glycerine. M. Follin applies a mixture of equal parts of Bismuth and Glycerine to the inflamed surface in chronic granular conjunctivitis, ciliary and glandular blepharitis. M. Dubout uses the same mixture as an application to eczema of the axillary, anal, or vulvar regions, and to chapped nipples, lips, and hands. M. Trousseau employs one part of Bismuth with three of Glycerine as an application to fissures of the anus.

555. In Leucorrha, Dr

Caby§ found the Nitrate applied by means of a speculum to the whole of the vaginal mucous membrane, most efficacious. The powder on a small piece of charpie was applied once a day. In Gonorrhoea and Gleet, Dr. Caby likewise found the Nitrate, suspended in water and used as an injection, a most valuable means of cure. The results of Mr. De Meric's || experience with it, however, in 140 cases, are not encouraging. He considers it, nevertheless, useful, especially in gleet.