1822. In Scrofulous Ophthalmia, It Has Been Advised; But Mr

Howard || states that he has derived no benefit from it. It deserves a fair trial. In Purulent Ophthalmia, it is favourably reported of by Dr. De Conde.¶ He found it especially useful in Ramollissement of the Cornea.

1823. In Phthisis, There Is No Medicine Of Such General Efficacy As Cod Liver Oil

Without adverting to the opinions of different eminent authorities, all of which are more or less favourable as to its value, it will be sufficient to quote the following statistical statement of Dr. C. B. Williams,** the result of his experience in its use: - Of 234 cases of which he preserved notes, there were 9 in which the Oil disagreed; 19 in which it appeared to do no good; and 206 in which its use was followed by marked and unequivocal improvement. Of the 206 patients, 62 had cavities in the lungs: all these improved materially under the use of the Oil. In 34, the improvement continued; in 11, it was only temporary; and in 17, the patients were lost sight of. In 100 patients, the tubercles had commenced to soften, but actual cavities had not formed; and both physical and general symptoms materially and rapidly changed for the better. The process of softening seemed arrested, as the moist rhonchi ceased, the dulness more or less disappeared, and, at last, vesicular breath-sound returned, and no physical signs whatever remained, excepting, perhaps, tubular expiration. Coincidently with these changes, the constitutional symptoms disappeared. In the remaining 44 patients, the disease was in the early stage, and the results were no less satisfactory. A perusal of the above statement will show that, out of 234 cases, 206 materially improved under the use of Cod Liver Oil; and that, even after cavities in the lungs had formed, more or less benefit resulted from its use. He advises it in doses of a tea-spoonful, gradually increased to a table-spoonful, thrice daily, in infusion of orange-peel. He concludes his valuable report by observing, that pure fresh oil from the liver of the cod is more beneficial in the treatment of pulmonary consumption than any agent, medicinal, dietetic, or regimenal, that has yet been employed. Powerful evidence in favour of its use is also adduced by Dr. John Hutchinson* and Dr. Walshe. One of the most remarkable effects of Cod Liver Oil is its power of increasing the weight. This is more marked in some than in others. Dr. J. Hutchinson instances the following examples; - In one instance, 41 lbs. were gained in 16 weeks; in another, 19 1/2. were gained in 28 days, and 10 lbs. in the succeeding 10 days; and in another case, 29 lbs. were added to the patient's weight in 31 days. Amelioration did not invariably follow an increase of weight, though the exceptions were rare. In other cases, where amelioration was still more considerable, and the progress of the disease appeared to be stayed, relapse occurred, and was followed by a rapid progress to a fatal issue. An aggravation of the symptoms, and a diminution of weight, were almost invariably coincidences. In a few cases, the symptoms improved, though the weight remained stationary, or even became slightly diminished. It is only natural to inquire in what manner Cod Liver Oil thus proves beneficial. The question cannot be answered with certainty; but it is probable that it acts by restoring a normal condition of the blood. This will appear evident from the following table; -

* Med. Times, Dec. 30, 1848.

Op. cit.

Med. Gaz., Aug. 22, 1851.

§ Gaz. Med. de Paris, 1837, p. 503.

|| Pathology of the Eye, p. 298. ¶ Ann. d'Oeulistique, 1858, vol. xl. ** Lond. Journ. of Med., Jan. 1849.

* Med. Times, Jan. 4, 1851.

Diseases of the Lungs, 1851.

Blood in health (Simon).

Phthisis (Simon).

Phthisis (Simon).

Phthisis,

after taking

Cod Liver

Oil for a long

period.

(Simon.)

Water................

Solids ..................

Fibrine.................

a trace.

Globulin.............

71 230

HAematin............

Albumen.................

Fatty matters............

4 200

Extractives and Salts ..

15 250

In some cases Ozonized Cod Liver Oil appears especially indicated with the view of reducing the frequency of the pulse (ante). It has been suggested that the explanation of the remarkable effect of Ozonized Oil in Phthisis may be found in the greater affinity which phthisical blood has with oxygen - an affinity which it also preserves when oxygen is in the allo. tropic form of Ozone.

1824. In Tabes Mesenterica, It Has Been Employed With Great Advantage

Under its use, the patient rapidly gains strength and flesh, the appetite returns, the tumefied belly becomes reduced, and a perseverance in this remedy is followed by a mitigation or removal of all the symptoms; the stools lose their clayey colour, and become bilious and healthy. Dr. Bennett* observes, that in no disease, with the exception of Rachitis, are the good effects of the Oil so well established as in this. In these cases, indeed, it is often very striking in its operation, curing the disease when every other remedy has failed. It should not only be given internally, but used as a liniment to the abdomen.

1825. In Rachitis, Dr

Bennett considers it the most efficacious of all remedies. M. Trousseau relates numerous cases in which it proved successful. He states that he generally found improvement at the end of eight or ten days, and that, in the majority of instances, a cure was effected in six weeks. He gave it in doses of f3ss. - f3iij. daily, mixed with sugar or syrup. Klencke also employed it successfully in three cases.