Green,|| of Peck-ham, advises a gargle composed of Cupri Sulph. gr. j., Aquae f., to be applied every hour.
1046. In Cancrum Oris, Aphthous Ulceration, and Gangrenous Affections of the Mouth, the Sulphate of Copper (gr. v.) finely powdered, and thoroughly incorporated with oz. ss. of honey, is an excellent application. Dr. Symonds¶ advises its application in substance to aphthous ulcers.
1047. In Chorea and Epilepsy, the Sulphate of Copper, given in small and gradually increasing doses, has occasionally been found effectual; but, as a general remedy, it is inferior in efficacy to the salts of Zinc or Iron. Dr. Hawkins** speaks highly of its efficacy in Epilepsy, given in 1/4 gr. doses with the Sulphate of Quinine. It failed, however, in the hands of Drs. Home, Hook, and others.
Reid, Simmons, and others, as producing less subsequent debility than Antimony or Ipecacuanha. Mr. Adair directs that the patient should first drink a pint of warm water, and then one grain of the Sulphate of Copper, dissolved in fss. of water, with one drop of Sulphuric Acid. This is to be taken every evening for three successive evenings, and then every morning. (On the value of this and other emetics in Phthisis, see Emetics.)
* Lectures, vol. ii. p. 216.
Mat. Med., vol. i. p. 874.
Compendium of the Materia Me-dica, 1838.
§ Brit, and For. Med. Rev., vol. ii. p. 568.
|| The Institute, Feb. 1, 1851. ¶ Lib. of Med., vol. iv. p. 35. ** Med. Gaz., vol. viii. p. 183. Med. Commentaries, vol. xviii. p 473.
1049. In Gonorrhoea, an injection of the following solution has been found useful: - Cupri Sulph. gr. iv. - v., Liq. Plumb. Diacet. fss., Aq. fiv., M.
xx. - gr. xxx. in Aq. Tepid. Oss.) has occasionally been found useful, when thoroughly injected into the vagina, thrice daily. The vagina should be previously washed out with soap and water. (Dewees.*)
Brodie speaks favourably of a long-continued course of the Sulphate, in small doses.
1053. In Superficial Hmarrhage from Leech-bites, the local application of the Sulphate is an effectual styptic. In Passive and Copious Epistaxis, a weak solution of the Sulphate injected into the nostril, proves serviceable. It is, however, inferior to Alum.
gr. j. in Aquae Camph. fl. oz. j., is occasionally serviceable. In Granular Conjunctivitis, the application of the Sulphate, in substance, to the inner part of the lids, is favourably spoken of by Sir W. Wilde.§
In Tinea Capitis, Dr. Graves || found a solution of the Sulphate (gr. x. ad Aq. fj a most useful local application. It should be applied in the manner advised in sect. 356. In Ringworm, a very effectual remedy is composed of Cupri Sulph. gr. xx., Pulv. GallAe gr. lx., Aq. fl. oz. j., M. In Scabies, a solution of the Sulphate (j. ad Aq. Oj.) has been successfully employed by Mr. Lloyd ¶ in a large number of instances. Previous to its use, the scabs should be rubbed off. In Ichthyosis, Mr. Erasmus Wilson ** speaks of the following as a useful application: - Cupri Sulph. j., Ung. Sambuci j., M. To be used twice or thrice daily. To Molluscum, Dr. Thompson applied with benefit the Sulphate in substance. To remove Warts, M. Cazenave employs a strong solution of this salt.
1056. To weak, irritable, and indolent Ulcers, the local application of a solution of Sulphate of Copper is attended with excellent effect. In the treatment of the ulcers of the Tenasserim Provinces, which are generally of a peculiarly obstinate character, I have met with great success by employing solutions of gradu; strengths, from one grain to ten grains in the ounce of water. At the commencement, the weakest solution is applied, twice daily; and when this ceases to occasion a feeling of heat in the ulcerated surface, the strength should be gradually increased by single grains, till the ten-grain solution is borne, by which time the ulcer is generally almost healed. In obstinate cases, these solutions may be alternated with others containing Nitrate of Silver, or Sulphate of Iron. To repress Exuberant Granulations, the Sulphate in substance should be employed. Alteratives should also be given internally.
* Diseases of Females, p. 75.
Lond. Med. Journ., vol. i. p. 266; vol. x. p. 149.
On Local Nervous Affections, Lond. Svo. 1837.
§ Dub. Quart. Joum., No. x. p. 97.
|| Clin. Lect., vol. ii. p. 357, and Dub. Joum., vol. xviii. ¶ Lancet, April 4, 1846. ** Diseases of the Skin, p. 383. Loc. cit., p. 388.