ss.; Iodide of Potassium oz. 1/4; Rectified Spirit Oj.). Dose, elv. - exx. This Tincture may be used as an external application to cause absorption in enlarged glands, diseased joints, chronic skin diseases, &c. It should be applied with a camel's-hair brush. The Compound Tincture of the Lond. Pharm. contains ss. of Iodine and j. of Iodide of Potassium to the pint.
* Lugol's Essays on the Effects of Iodine in Scrofulous Diseases, translated by Dr. O'shaughnessy, Lond. 8vo, 1831; and Lugol's Researches, &c., on Scrofulous Diseases, by Dr. Ranking, 1844, Lond. 8vo. From these two valuable works, a great part of this article is compiled. - E. W.
Brit, and For. Med. Rev., June 1871.
Gaz. Med. de Paris, 1860.
xxxij.; Iodide of Potassium gr. xxxij; Proof Spirit fl. drm. j.; Prepared Lard oz. ij.). The Ointment of the Lond. Pharm. contains 3ss. of Iodine, and 3j. of Iodide of Potassium to gij. of Lard.
Dose of Iodine, gr. J, gradually increased to gr. j. (See sect. 1572.)
1571. The alleged ill effects of Iodine are: - 1. That it causes emaciation of the body generally. This is contrary to the experience of Lugol,* who, from a large number of observations, concludes - 1, that emaciated females acquired a state of embonpoint; 2, that corpulent women did not become emaciated; and 3, that those not belonging to either of the preceding classes lost nothing of their middle state, but gained strength and improved health. Dr. Ranking adds that his own observations quite bear out the remarks of Lugol. 2. That it causes emaciation, of the mamma in the female and of the testis in the male. There are cases recorded by Cullerier and others in which these effects have been observed; but so rare are their occurrence that neither Lugol, Magendie, Ranking, nor Dr. Davies, § of Hertford, ever met with a single example, although they have respectively employed this agent in a very large number of cases. In Cullerier's patients the organs resumed their natural size and functions when the medicine was discontinued. Although I have employed this remedy extensively, and continued its use for weeks and even months, I have never met with an instance of emaciation of these organs. 3. That it produces salivation. This effect is much more common than either of the preceding. Many instances of it are on record. It differs from mercurial salivation in not being attended with fetor of the breath, by the teeth remaining firmly fixed, by the absence of ulcers of the gums,|| and by disappearing when the medicine is omitted. It has more frequently been observed when a course of Mercury has preceded the use of Iodine. 4. That it occasions Catarrhal symptoms, HAemoptysis, gastric irritation, and general disturbance of the system. These effects, it is now generally admitted, only occur in persons who, from peculiar idiosyncrasy, are unable to take the medicine in any form or dose (such cases, however, are rare), or where the remedy has been exhibited in injudiciously large doses.