In a memoir presented to the Academy of Sciences of Paris, by Drs. Lalesque and Gouzee, in 1835, it was stated that the Chloride (Hypochlorite) of Soda possessed as active and as certain febrifuge properties as Quinine, and that it was an eligible substitute for that alkali. A committee was appointed to examine the question, and the results of the inquiry are thus summed up: - 1. The Chloride of Soda actually possesses febrifuge properties. 2. It is far from producing the certain and energetic effects of Quinine. 3. It cannot, therefore, replace that article in severe intermittents. 4. It is not irritant. 5. It may be had recourse to in mild cases with advantage. 6. The diminution of the intensity of the paroxysms during its use augurs favourably, but does not always announce an approaching cure. 7. It exercises a favourable influence over engorgements of the spleen. 8. The ordinary prescription has been 3ss. of the Chloride dissolved in fiv. of water daily. The patients have taken this quantity, so that the last dose should be administered shortly before the expected paroxysm.
* Lectures, vol. ii. p. 822.
Revue Medicale, Feb. 1836.
2561. In Syphilitic Eruptions of the Scalp, Lepra, Psoriasis, Lichen, Eczema, and Impetigo, Mr. Acton employs, in the early stage, a diluted solution of the Chloride. The parts should be first well moistened with this, then carefully dried and sprinkled over with finely-powdered Calomel. Under this treatment, he states that the eruptions rapidly disappear. In the non-Syphilitic forms of these affections, as well as in Pruritus and Tinea Capitis, the diluted solution (f3vj. ad Aq. fxij.) has been found useful. Dr. Todd found it highly serviceable in Ecthyma Febrile.