6. The Minimum Dose (I

e. a dose which, if given continuously, affects the conjunctiva in the slightest possible degree) should be persevered in with unremitting regularity for as many months after the disappearance of the disease as it had previously existed years. This is necessary to prevent a relapse.

7. Should the disease appear to advance instead of recede during any period of the minimum dose, the course should not be intermitted on this account. Leeches or purgatives in the sthenic, and Quinine, with generous living, in the asthenic cases, will generally be sufficient.

In order to test more strictly the value of the remedy, Mr. Hunt occasionally intermitted the course, and with the most uniform result, viz. a relapse of the disease. For the same purpose, he abstained from all external applications (leeches excepted), and states that he never found them necessary to the cure.

Dr. T. M'Call Anderson,* in advocating the use of Arsenic in Eczema, recommends that it be given in doses of ev. of Liq. Arsenic. thrice daily, and at the end of a week or so the dose is to be increased by a drop every second or third day. He does not think it necessary to stop if irritation of the eyes or slight puffiness of the face are induced. If these symptoms, however, become aggravated, and are accompanied by pains in the stomach and head, anorexia, and nausea, the dose should be diminished or omitted for a few days. But he recommends that its administration be not stopped altogether because these physiological effects are produced. In the case of infants at the breast, he prescribes Arsenic for the mother. Dr. Begbie also thinks that, in order to procure the virtues of arsenic as an alterative, it is necessary to push it to the full development of the phenomena which indicate its peculiar action on the system.

406. In Relapsing Pemphigus, Arsenic Appears To Possess Almost Specific Virtues

Mr. Hutchinson states that in his experience Arsenic almost invariably cures the disease at once, but that relapses may be expected to take place once or twice in the twelvemonth. If, however, Arsenic be again resorted to, the patient's health gradually improves, and each successive attack becomes milder.

* Med. Times and Gaz., June 27, 1803, p. 661. Contributions to Practical Medicine, p. 270.

Med. Times and Gaz., Jan. 2, 1864, p. 10.

407. In Lupus Exedens, Mr

Hunt* also made extensive trials with Arsenic, given as above. He found it highly successful'. In Lupus Non-Exedens its value is trifling.

408. In Chronic Lichen Agrius, Dr

Houghton regards Arsenic, in the form of Liquor Arsenicalis, as the best internal medicine. He advises it in doses of gutt. iij. - viij. daily.

409. In Sycosis, Dr

Wright strongly recommends the follow-ing mixture, having experienced much benefit from it: -409 In Sycosis Dr 40 Infus. Gentian. fviij., Liq. Arsenicalis, Liq. PotassAe aa f3j., M. sumat coch. amp. ij. ter in die.