1986. In Ovarian Irritation, Dr

Churchill j| found the local application of Opium very effectual. He prescribes some balls or pessaries, each containing gr. ij. of Opium, 3ss. of white wax, and 3iss. of lard. The whole, when mixed together, forms a ball about the size of a large marble; this is placed at the upper end of the vagina by means of a speculum, and the patient is directed to remain in bed for the remainder of the day. Dr. Churchill adds that he has tried this remedy in a considerable number of cases, and with almost invariable success; that since he has adopted it, he has rarely found it necessary to bleed or blister; and that he recommends it, with considerable confidence, to the profession. If a relapse occur after the first application, a second was found to remove it effectually.

1987. In threatened Abortion, Opium proves in some instances of great value; but caution is necessary in its use. Dr. Lever ¶has ably pointed out those cases in which it may be used with advantage, and those in which it is inadmissible. When abortion occurs from ftal disease or imperfection, so that the premature emptying of the uterus is but an effort of nature to get rid of that which she cannot accomplish, - if, with the discharge, there is a patent state of the os uteri, and if the cervix be soft and loose, the exhibition of Opium will do harm by retarding the emptying of the uterus, which must sooner or later take place. When, however, it arises from accident, or from mental causes, or from those which may be said to be due to habit, he has known the exhibition of Opium by mouth, or, what is better, a cold starch injection with Opium, thrown into the bowel, and repeated every night or oftener, according to existing circumstances, followed by the best results. Application of cold, perfect quietude, and unstimulating diet should be enforced. When, however, abortion has taken place, especially if the event has been attended with much loss of blood, Opium, in almost every case, may be given not only with safety, but with benefit. It will then allay excitement, tranquillize the circulation, and procure sleep.

* Bull, de Therap., 1857, vol liii.

Lancet, May 22, 1858.

Ibid., Feb. 2, 1881.

§ lib. of Med , vol. iv. p. 312.

|| Dub. Journ. of Med. Science, Aug. 1851.

¶ Med. Gaz., Dec. 23, 1850, from which I have drawn largely in this and the few following sections.

1988. In those Pains which precede the establishment of Labour in the latter weeks or months of Gestation, Opium may be given with great advantage. ''Many a patient," observes Dr. Lever, "has been carried on to the full end of her term, who, but for it, would have prematurely parted with her offspring." He mentions the case of a lady, who, six weeks from the completion of her full term, fell on her back. The liquor amnii was evacuated. In addition to absolute quietude, she took Opium at irregular intervals, till the end of the ninth month, when a living child was born. She had miscarried twice previously.