Local applications of it are useful only when the disease is limited to the external auditory passages. When it depends upon inflammation or ulceration of the internal structures, injections may create serious disturbance, and should not be employed; but the internal use of the solution (No. 1) may be persevered in with great advantage, giving strength and tone to the system.
* Appendix to O'shaughnessy's Trans, of Lugol, op. cit. p. 188.
Op. cit, p. 301.
stage; and Iodine injections (No. 2) into the fistulous tracks after the abscess has burst.
1), recommends the solution (No. 3) to be daily applied to the conjunctiva, by means of a syringe. Great success is stated to have attended this practice; but the one which I have employed for some years with manifest advantage is that proposed by Dr. Furnival,* of Hertford. The eyelid is put on the stretch, and the Tincture of Iodine (L. Ph.) applied to the external surface of the eyelids. It relieves the profuse lachrymation and the photophobia in a remarkable manner. Dr. Furnival states that he has employed it in this manner for many years, and always with decided benefit: he adds, in the early stages it will altogether, and speedily, arrest the morbid action; and in the latter periods, it will greatly lessen, if not entirely remove, opacities of the cornea, which have resisted all other remedies. The Tincture should be applied once daily with a camel's-hair brush. Iodine (No. 1) should be given internally; and, at the same time, a generous diet, free exposure to the light, and the disuse of dark rooms and of shades, are advised.
1586. In Tubercular Meningitis, or Acute Hydrocephalus, Iodine has been used with benefit. Drs. Christie and Woniger relate two cases which had reached the paralytic stage, but which recovered under the external and internal use of Iodine. Dr. Bennett states that he has derived decided benefit from Iodine and its preparations, in this disease; and Dr. Willshire bears similar testimony. The former advises the use of Iodine, externally and internally, in the early stages of the disease, before there is much evidence of inflammation and congestion. He applies the Iodine ointment to the shaven scalp, and gives, internally, gr. 1/10 of Iodine with gr. iij. of Potas. Iod. in solution, every three hours. This, with turpentine enemas, will be found in most cases a palliative, and, in some, a curative mode of treatment. Dr. Rilliet § advises the use of Iodine frictions to the shaven scalp in the second and third stages of the diseases. Dr. Winn || relates a case of Chronic Hydrocephalus treated with injection of Iodine (Tr. Iod. exiv., Aq. fij.) subsequent to paracentesis. Though the case ended fatally, it would seem to prove that Iodine may be injected into the brain without causing any poisonous or other ill effect. The practice is not advocated.
1587. In Phthisis, Iodine has been employed with much confidence, in consequence of the benefit derived from it in other forms of tuberculous disease. Drs. Morton (U.S.), Gairdner,
* Lancet, vol. i. 1842-43, p. 405. Brit, and For. Med. Rev., April 1844.
Med. Times, vol. xvi. p. 505. § Prov. Joum., Feb. 20, 1850. || Lancet, Nov. 3, 1855.
Baron, and others, have reported favourably of it. Dr. C. B. Williams * states that he believes it capable of promoting the removal of phthisical lesions in their early stage, and of retarding their increase; and adds, that for twelve years, he has used the subjoined formula with benefit in incipient cases: - Potas. Iod. gr. ij. - iij., Liq. Potas. exx. - xxx., Aq. fiss., ter in die sumend. Sedatives or expectorants were added, as required. Sir C. Scudamore strongly advocated Iodine inhalations; and, for this purpose, employed the subjoined mixture: - Iodin. gr. v., Potas. Iod. gr. iij., Aq. Dest. fv., Alcohol f3ij., T. Conii f3vj., M. Of this, f3j. - f3ij. is directed to be mixed with water, at 120° F., and inhaled for fifteen or twenty minutes, thrice daily. Dr. Snow, after a fair trial, corroborates the opinion commonly entertained, that little benefit is to be derived from it when thus employed. It is occasionally useful as a palliative. As a remedy for Phthisis, Iodine is greatly inferior to Cod Liver Oil, the latter having almost entirely superseded its use. Piorry § reports favourably of Iodine inhalations in Phthisis; but as the majority of his patients took from gr. xx. to gr. lx. of Iodide of Potassium daily whilst under treatment, it is manifestly incorrect to ascribe all the benefit - if any - to the Iodine inhalation. If inhalation be deemed advisable, a few drops of the Tincture (Brit. Pharm.) added to half a pint of hot water may be used. Iodine inhalation has occasionally been found of use in some forms of Chronic Bronchitis.
1588. In Bronchocele or Goitre, Iodine is peculiarly efficacious, but it does not deserve the character of a specific, which has been attributed to it by some. It was first introduced into practice by Coindet, of Geneva, in 1820, and was subsequently extensively employed by Dr. Manson,|| of Nottingham. Of 120 cases treated by him, 87 were cured, 10 much relieved, and the remainder were discharged unrelieved. He employed the following formulae: - Iodin. gr. xxiv., Spt. Vin. Reet, fj., M. sumat. gutt. xv. - f 3ss. ex aq. ter in die. ℞ T. Iodinii (ut supra) f 3j., Liniment. Sapon. fj., M. ft. liniment. The latter was applied externally twice daily. The value of Iodine in this disease is universally admitted, but it occasionally fails to effect either a diminution in size, or a removal of the tumour. It is inferior to the Iodide of Mercury (q. v.).
1589. In Hypertrophy of the Tonsils, Iodine, employed externally and internally, proves highly serviceable. The aqueous solution (No. 1) may be given internally, and the Tincture applied externally to the throat. The enlarged tonsils themselves may
* Lib. of Med., vol. iii p. 192.
+ Cases illustrative of the Power of Iodine, &c. in Tubercular Phthisis, Lond. 1834.
Lond. Journ. of Med., Feb. 1851. § Comptes Rend., Jan. 24, 1854. || Med. Researches on Iodine in Bronchocele, Loud. 1825.
also be painted with the Tincture. The application should be repeated every second or third day.