10. The Following Valuable Observations Of

Dr. Prout merit especial attention. " The stimulating effects of Mercury," he observes, " may be analogically illustrated by the stimulating effects of dram-drinking. As the stomach accustomed to ardent spirits will scarcely tolerate any weaker beverage, so the liver accustomed to the stimulus of Mercury will hardly respond to any other influence. Those, therefore, who in early life have on all trivial occasions resorted to the powerful stimulus of Mercury, are usually obliged, like early dram-drinkers, to persist in the baneful habit. The most superficial observer must have noticed, that patients who habitually take Calomel are more than ordinarily subject to biliary attacks, as they are termed, and that these will rarely yield to any other remedy. Nor is this its only fault; the habitual use of this remedy exerts positive mischief on the assimilating functions, and on the kidneys of some individuals." He adds, " I can truly say, that a large proportion of the most inveterate dyspeptic and urinary diseases which I have seen, have been distinctly referable to the abuse of Mercury. It may be objected, that many individuals begin the use of Mercury early, and continue it with the same evident advantages to extreme old ago; to this it is answered, that many persons commence the use of spirituous liquors at an early age, and continue to use them to extreme old age; but no one will say that such ought to become the rule. The same remark is strictly applicable to the abuse of Mercury. The object of these remarks is to imprest on the reader the important fact, that when it hat no real diteate to combat, Mercury it liable to give occasion to disease: and, consequently, to warn him against the indiscriminate use of this active remedy on trivial occations, and in all diseases and constitutions."

1365. Mercury is either contra-indicated or injurious - 1, in all forms of tubercular disease, viz., Scrofula, Phthisis, Scrofulous Iritis, and in all diseases, including Syphilis, occurring in persons of a strongly marked scrofulous diathesis;

2, in Phagedenic Ulceration; 3, in Gout, and Arthritic Inflammation of the Eyes; 4, in Scurvy, and in persons of the Scorbutic diathesis: Dr. Budd asserts that even in Syphilis occurring in persons of this habit, the employment of Mercury is unsafe and injurious; 5, in Inflammatory Dropsy, Dr. Todd§; cautions the practitioner against the use of Mercury, regarding it not only as useless, but injurious; 6, in Inflammation of the Bladder, Sir B. Brodie || says that Mercury is certainly not beneficial and is often injurious; 7, in Diabetes, Dr. Prou¶ says that he has almost invariably seen it produce mischief; 8, in Granular Disease of the Kidney, it is condemned by Christison** and most subsequent writers. It should not be given in Dropsy dependent on Granular Disease of the Kidneys. As a rule, it should not be administered when the urine is albuminous. 9, in Enlargement of the Spleen, Dr. Abercrombie gives strict injunctions against it; and 10, in all AnAemic states from whatever cause arising. On this subject, the reader will do well to consult Dr. Habershon's work, "On the Injurious Effects of Mercury in the Treatment of Disease." (London, Svo, 1860.)