2346. In Cholera, Quinine Is Advised By Dr

Bell, under a fancied resemblance which he considers to exist between this disease and intermittent fever. Dr. James Bird also recommended it in combination with Iron, Camphor, and Opium, in order to support the powers of the nervous system *and of the heart, and it has been occasionally prescribed by others, without any definite view whatever. In some instances it is stated to have proved eminently successful. Dr. Maxwell} regards it as a preventive. He directs it to be taken in doses sufficiently large to cause ringing in the ears, with wine, &c, as hot as the patient can bear.

2347. In Diarrha, particularly when it assumes an intermittent or periodic type, Quinine, in combination with other remedies, appears to exercise a favourable influence. The Citrate of Iron and Quinine has proved very effectual in the Infantile Cholera (so common in the neighbourhood of London) in the hands of Dr. Cormack, of Putney; and Dr. Evans, of Tazewell (U.S.), states that it enters into the most famous nostrums in use in Mexico, against this disease.*

* Clin. Lect., vol. ii. p. 520. On Cholera and Intermittent Fever, 1849.

On the Pathology of Cholera, Lond. 1849. § Med. Times, vol. xix. p. 196.

2348. In Dysentery, Cinchona has long been esteemed in the treatment of the advanced stages, and is recommended by Clark, Douglas, Huxham, Pringle, Cullen, and others. The last-named physician limited its use to the disease when it assumes a remittent form. In the asthenic and malignant varieties, and also in the advanced stages of the disease, when the vital powers and nervous energy are much exhausted, Quinine, with small doses of T. Opii, may prove very serviceable. It may also be advantageously combined with Camphor.

2349. As an Anthelmintic, especially in cases of Ascarides lumbricoides, the value of Quinine has been pointed out by Dr. Delvaux. For children between two and ten years, the dose ranges from grs. iij. - vj.; for adults, grs. ix. in the twenty-four hours. Injections containing the Sulphate, every evening, he found effectual in removing thread-worms from the rectum; and he likewise mentions two cases in which taenia were expelled under its use. As far back as 1764, Van Doeveren, of Groningen, pointed out the anthelmintic properties of Cinchona.