This section is from the book "Practical Materia Medica And Prescription Writing", by Oscar W. Bethea. Also available from Amazon: Practical Materia Medica and Prescription Writing.
Latin, Antipyrina (Gen., Antipyrinae)
Eng., Antipyrine. Synonym, Phenazone.
Usually a colorless crystalline powder.
Almost odorless and tasteless.
In less than 1 part of water. In 1.3 parts of alcohol.
Acids and drugs containing tannic acid in appreciable amounts; alkalies, salts of iron, mercury, lead and arsenic; iodine and iodides; sodium bicarbonate and salicylate; alum, ben-zoates, phenol, cinchona alkaloids, resorcin,. spirit of nitrous ether, thymol, etc.
5 grains (0.3 Gm.).
Antipyretic, sedative, analgesic.
Employed in the treatment of fevers, headache, neuralgia, whooping-cough, etc.
Antipyrine is so generally incompatible with other drugs that it is better to remember the few desirable agents with which it can be prescribed to advantage. This would include few others than caffeine, sodium bromide and flavored syrups. It is the most soluble of the common coal-tar antipyretics. It is prescribed alone in powders, capsules or in solution.
Antipyrine may be prescribed as:
or | |||
Antipyrinae.............................................................. | gr. xl | 2 | 5 |
Elix. Aromatici................................................... | q. s. | 30 | 0 |
M.
Teaspoonful in water every two hours when necessary.
A frequent combination of antipyrine is shown in the following prescription for the paroxysmal stage of whooping-cough: For a child 4 years old:
or | |||
Antipyrinae........................................................... | 3ss | 2 | |
Sodii Bromidi..................................................... | 3j | 4 | |
Syr. Tolutani................................................... | q.s | 60 |
M.
Teaspoonful in water every two hours until relieved.
Tinctura Belladonna; Foliorum is sometimes added.
As a hypnotic, analgesic, cough sedative and antispasmodic:
or | |||
Codeinae Sulphatis.......................................... | gr.ss | 03 | |
Antipyrinae.................................... | gr.xvj | 1 | 00 |
Syrupi Aurantii....................................... | q.s | 60 | 00 |
M.
Teaspoonful every two hours when needed. (Child 2 years old).
It is sometimes used by the physician as a local application, as in the following formula used by the rhinologist on cotton applicators to relieve congestion of the nasal mucosa:
or | |||
Cocainae Hydrochlor..................................... | .gr. v | 3 | |
Antipyrinae........................................................ | gr.xv | 1 | 0 |
Aquae Dest..................... | q.s | 30 | 0 |
M.
Formula.
See Opium, p. 242.
 
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