This section is from the book "Practical Materia Medica And Prescription Writing", by Oscar W. Bethea. Also available from Amazon: Practical Materia Medica and Prescription Writing.
In the treatment of coryza:
or | |||
Ext. Belladon. Fol. ......... | gr. ss | 03 | |
Camphorae.............. | gr. vj | 40 | |
Quininae Sulph., | |||
aa.gr. xij | 80 |
M. ft. cap. no. xij.
One every half-hour for four hours, then one every three hours.
1Shoemaker: Materia Medica and Therapeutics. 2 Musser and Kelly: Practical Treatment.
In the treatment of grip, cold, etc.:
or | |||
Caffeinae Citratae............ | gr. x | 65 | |
Quininae Hydrobrom............. | gr. xx | 1 | 30 |
Acidi Acetylsalicyl................ | gr. L | 3 | 00 |
M. ft. cap. no. xvj.
One every two hours till eight (8) are taken each day.
In the treatment of chronic heart disease:
or | |||
Digitalis Pulv, | |||
Quininae Hydrochlor............. | āā. gr. xv | 1 | 0 |
Ext. Valerianae.............. | 3j | 4 | 0 |
M. ft. cap. no. xxx.
One three times a day.
The principle in preparing a so-called"tasteless"quinine is to use a salt that will dissolve only to the smallest possible extent, so it will not come into contact with the special nerve-endings in such form as to be appreciated. The sulphate is probably the best salt for this purpose. The tannate is less bitter but has to be given in large amounts and at least is slower and more uncertain in action.
It is usually possible to ascertain the preference of the child as to flavor. Glycyrrhiza may be distinctly disagreeable to some, while syrup of chocolate would be very acceptable.
Some adults and practically all small children are unable to swallow capsules. The prescriber should always ascertain as to this matter before writing his prescription. If patient is a child 8 to 10 years of age, but has never been tried on capsules, the prescription may be written for that form and the nurse instructed to empty them and administer in syrup of chocolate if the capsules cannot be swallowed. This method is sometimes desirable, anyway, as, for example, when other agents are ordered with the quinine salt that cannot well be put in solution. To illustrate: The following has been used for a child 6 years old, to follow the customary three days' intensive quinine treatment for malaria:
or | |||
Strychninae Sulph............... | āā. gr. 1/3 | 002 | |
Quininae Sulph., | |||
Ferri Reducti..................... | āā. gr. l | 3 | 000 |
M. ft. cap. no. l.
One after meals as directed.
1 Musser and Kelly: Practical Treatment.
A"tasteless"syrup for administration to a child:
or | |||
Quininae Sulphatis............ | gr. xvj | 1 | |
Syr. Eriodictyi Arom............ | q. s. | 60 |
M.
Five (5) teaspoonfuls each day as directed. (Shake-label.)
Syrup of glycyrrhiza or syrup of chocolate may be ordered as the vehicle in the above.
In the treatment of malaria (child 6 years old):
or | |||
Quininae Sulphatis.............. | gr. xxx | 2 |
Ft. cht. no. xviij.
Six (6) powders in chocolate syrup each day as directed.
These are frequently desirable for adults and sometimes for children. Some combinations are shown in the following:
As a bitter tonic to follow the intensive treatment of malaria:
or | |||
Quininae Sulphatis ............... | 3iiss | 10 | |
Tinct. Ferri Chlor. ................ | f3vj | 23 | |
Liq. Acidi Arsenosi............. | f3ij | 8 | |
Aquae................ | q.s. | 180 |
M.
Teaspoonful in water after meals.
or | |||
Quininae Sulphatis.......... | 3iiss | 10 | |
Acidi Sulph. Arom............. | f3ij | 8 | |
Elix. Aromatici.............. | q. s. | 180 |
M.
Teaspoonful in water before meals.
This method is sometimes employed, particularly when it is desirable to get the patient rapidly under the influence of the drug. Quinine Hydrochloride is sometimes used but Quinine Dihydrochloride is even more desirable for this purpose. It is soluble in less than its own weight of water.
Quinine and Urea Hydrochloride is soluble in its own weight of water, so is a valuable form for hypodermic use. Hypodermic employment is, of course, confined to the physician himself. He may use the tablets and prepare the solutions extemporaneously or order them as follows:
or | |||
Quininae Dihydrochlor........... | 3j | 4 | 0 |
Aquae Destillatae............ | q. s. | 15 | 0 |
M.
Or:
or | |||
Quin. et Ureae Hydrochlor........... | gr. xxx | 2 | 00 |
Aquae Dest............... | q.s. f3j | 4 | 00 |
M.
Formula.
These solutions should be given largely diluted and even then there is frequently slow absorption, local irritation, and, it is claimed, sometimes even tetanus.
Considered by many as preferable to the hypodermic method. The solutions, as just stated for hypodermic use, may be employed only largely diluted with normal saline.
The administration of quinine in the Murphy drip for constitutional effect is probably practical and worthy of more thorough investigation.
The salts of quinine are sometimes used in enemas, as the following for amebic dysentery:
or | |||
Quininae Sulphatis......... | 30 |
Ft. cht. no. x.
Use one to 1/2 gallon of warm water as directed.
Or the following for pinworms in a child:
or | |||
Quininae Bisulphatis............. | gr. xxx | 2 | |
Quassiae............... | 30 |
Make a tea with 1/2 gallon hot water and use as directed.
Quinine and its salts are sometimes used in hair tonics, ointments, etc.
In the treatment of alopecia:
or | |||
Resorcinolis........ | gr. lxxx | 5 | 0 |
Quininae................ | gr. xv | 1 | 0 |
Olei Ricini................... | xx | 1 | 3 |
Alcoholis................... | q. s. | 120 | 0 |
M.
Apply as directed.
1 Stelwagon: Diseases of the Skin.
 
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