This section is from the book "Practical Materia Medica And Prescription Writing", by Oscar W. Bethea. Also available from Amazon: Practical Materia Medica and Prescription Writing.
Latin, Cocaina
Eng., Cocaine. An alkaloid obtained from Ery-throxylon Coca.
1/4 grain (0.015 Gm.).
Eng., Cocaine Hydrochloride.
Colorless prisms, flaky leaflets or white powder.
Odorless and having a bitter taste.
In 0.4 part of water and 3.2 parts of alcohol.
Alkalies, bromides, iodides, mercury salts, chloroform, etc.
1/4 grain (0.015 Gm.).
Cocaine Hydrochloride is used almost to the exclusion of all other preparations from coca.
Local anesthetic, antiemetic, stimulant.
Chiefly employed to produce local anesthesia for surgical work; also used for pruritus, eczema, hemorrhoids, anal fissure, etc. Used to counteract unpleasant effects of other agents in the treatment of eye diseases, rhinitis, etc.
By Mouth.-It is not often prescribed in this way except to allay gastric irritability. The following will illustrate:
1 Ashton: Practice of Gynecology.
2 Shoemaker: Materia Medica and Therapeutics.
or | |||
Cocainae Hydrochlor............ | gr. j | 065 | |
Acetanilidi............. | gr. x | 650 | |
Cerii Oxalatis................ | gr. xx | 1 | 300 |
M. ft. cht. no. iv.
One every two hours when indicated.
It is used either alone or with such agents as Sodium Chloride or Adrenalin Chloride. Hypodermic solutions are not ordered for the patient's use, and the physician frequently employs tablets to make the solution extemporaneously. They may be ordered as follows:
As a local anesthetic:
or | |||
Cocainae Hydrochlor......... | gr.j | 065 | |
Sodii Chloridi................ | gr. iij | 200 | |
Adrenalin Chlor. (Sol. 1:1000)............ | v | 300 | |
Aquae Destil. Ster................. | q. s. | 30 | 000 |
M.
Unless the solution is for immediate use, the adrenalin should be omitted from the prescription, and added just before the preparation is employed.
To prescribe percentage solutions of cocaine:
or | |||
Cocainae Hydrochlor............. | gr. xviij | 1 | 2 |
Aquae Destil. Ster................ | q. s. | 30 | 0 |
M.
Four per cent. solution cocaine hydrochloride.
Cocaine is frequently a constituent of local applications.
In the treatment of erythema venenatum:
or | |||
Cocainae Hydrochlor............... | gr. x | 65 | |
Adrenalin Chloridi (1:1000)............ | 15 | 00 | |
Aquae Rosae....................... | q.s. | 180 | 00 |
M.
Apply every two hours.
l Ashton: Practice of Gynecology.
2 White and Martin: Genito-urinary and Venereal Diseases.
3 Ohmann-Dumesnil: Diseases of the. Skin.
In the treatment of conjunctival inflammation as.caused by foreign particles, etc.:
or | |||
Cocainae Hydrochlor........... | gr. ij | 13 | |
Adrenalin Chlor. (1:1000).......... | v | 30 | |
Acidi Borici.............. | gr. x | 60 | |
Aquae Destil. Ster................. | q. S. | 30 | 00 |
M.
Drop in eye every three hours till relieved.
In the treatment of turgescent rhinitis:
or | |||
Cocainae Hydrochlor.......... | gr. v | 3 | |
Antipyrinae......... | gr. xv | 1 | 0 |
Aquae Dest................ | q. s. | 30 | 0 |
M.
For physician's use.
This is usually applied on long, slender rolls of absorbent cotton made by rolling cotton around a probe or applicator and then slipping it off. They are dipped into the solution and inserted in the nose and allowed to remain a few minutes.
In the treatment of erythema scarlatiniforme:
or | |||
Cocainae Hydrochlor............ | gr. iv | 26 | |
Acetanilidi.......... | gr. xx | 1 | 30 |
Zinci Oxidi............. | 3iss | 6 | 00 |
Ung. Zinci Oxidi......... | q. s. | 60 | 00 |
M.
Apply thin on a cloth.
In the treatment of herpes progenitalis:
or | |||
Cocainae Hydrochlor........... | gr. j | 065 | |
Mentholis............. | gr. xij | 800 | |
Adipis Lanae Hyd............... | q. s. | 15 | 000 |
M.
Apply locally.
1 Ohmann-Dumesnil: Diseases of the Skin.
2 White and Martin: Genito-urinary and Venereal Diseases.
In the treatment of pruritus ani:
or | |||
Cocainae Hydrochlor........... | gr. x | 65 | |
Phenolis................ | gr. xx | 1 | 30 |
Petrolati............. | q. s. | 30 | 00 |
M.
Apply locally.
 
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