Eng., Hyoscyamine Hydro-bromide. The hydrobromide of an alkaloid obtained from Hyoscyamus and other related plants.

Solubility

Soluble in water or alcohol. Average Dose.- 1/200 grain (0.0003 Gm.).

Therapeutic Action

Sedative, antispasmodic, anodyne, de-liriant and mydriatic.

Uses

Principally employed as antispasmodic for whooping-cough, asthma, croup, etc. Used in combination with other agents for hysteria, alcoholic psychosis and related conditions. A common constituent in purgative preparations to prevent griping. Hyoscine is employed in the treatment of alcoholism.

Administration

Extract of Hyoscyamus is more frequently used in the form of the unofficial powdered extract.

The tincture is the preparation used in fluid combinations. The alkaloidal salt is sometimes used by physicians, but seldom prescribed, and frequently disappointing.

In the treatment of palpitation in hysterical subjects:

Hyoscyaminae Hydrobromidum 815

or

Strychninae Sulph.................................................

gr. 1/3

02

Zinci Valeratis.............................................

gr. x

65

Ext. Sumbul...................................................

gr. x

65

Ext. Hyoscyami............................................

gr. v

32

M. ft. cap. no. x.

Sig

One after each meal.

In a purgative mixture, to prevent griping:

Hyoscyaminae Hydrobromidum 816

or

Hydrarg. Chlor. Mitis,

Rhei Pulv.,

Ext. Fel. Bovis...................................................

āā. gr. v

320

Ext. Hyoscyami Pulv.......................................

gr. j

065

M. ft. cap. no. iij. Sig.-One every hour.

In the treatment of colds, etc.:

Hyoscyaminae Hydrobromidum 817

or

Acetphenetidini................................................

gr. xxx

2

0

Ammonii Carb................................................

gr. xx

1

3

Tinct. Hyoscyami....................................

f3j

4

0

Mellis Depur................................................

Hyoscyaminae Hydrobromidum 818

45

0

Spir. Vini Gallici............................................

q. s.Hyoscyaminae Hydrobromidum 819

90

0

M.

Sig

(Shake-label).

Tablespoonful in water every four hours.

1 Anders: Practice of Medicine.

This does not make an elegant-looking mixture, but seems to be clinically of value.

As a sedative in the treatment of violent cough:

Hyoscyaminae Hydrobromidum 820

or

Heroinae Hydrochlor...................................

gr. j

065

Ammonii Chlor..............................................

3j

4

000

Tinct. Hyoscyami .................................

f3iij

12

000

Syr. Pruni Virg..........................................

q. s.Hyoscyaminae Hydrobromidum 821

60

000

M.

Sig

Teaspoonful every two hours till relieved.

In the treatment of cough:

Hyoscyaminae Hydrobromidum 822

or

Codeinae Sulph................................................

gr. iij

2

Tinct. Hyoscyami......................................

f3iij

12

0

Syr. Tolutani................................................

Hyoscyaminae Hydrobromidum 823

15

0

Aquae...............................................

Hyoscyaminae Hydrobromidum 824

90

0

M.

Sig

Teaspoonful every three hours.

In the treatment of cystitis, whooping-cough, etc.:

Hyoscyaminae Hydrobromidum 825

or

Tinct. Hyoscyami...........................................

f3ss

2

Potassii Citratis............................................

3j

4

Aquae...............................................................

q. s.Hyoscyaminae Hydrobromidum 826

120

M.

Sig

Teaspoonful in water every three hours.

In a sedative mixture:

Hyoscyaminae Hydrobromidum 827

or

Chlorali Hydrati

3j

4

Sodii Bromidi................................................

3ij

8

Tinct. Hyoscyami........................................

f3ij

8

Aquae Chloroformi....................................

q. s.Hyoscyaminae Hydrobromidum 828

30

M.

Sig

Teaspoonful every four hours till relieved.