(Active Ingredients. - The leaves or rather fronds of Thuja contain Thujin, C20H12O12, and Thujigenin, C14H1207, discovered by Ro-chelder and Kawalier in 1858. Thujin forms citron-yellow shining microscopic crystals, slightly soluble in cold, better in hot water, and freely in alcohol. Thujigenin is amorphous. There is also a camphoraceous oil and wax and a peculiar form of tannin called pini-tannin.

Physiological Action. - Little has been recorded on this subject, except by the homoeopaths, who in one treatise devote a hundred and fifty pages to the subject.)

Therapeutic Action. - The common arbor vitae is considered to partake of many of the properties of savin. It is useful in rheumatic and arthritic pains, and in ulcerated surfaces, especially about the corona glandis. My own experience induces me to recommend it in the highest terms for the cure of warts with a narrow base and pendulous body. These may occur upon any part of the surface, and often have an hereditary history. Many of them are removed by cleanliness and the external application of nitrate of silver, glacial acetic acid, or the acid solution of nitrate of mercury, or by cutting off the growth with a pair of scissors, and dressing the part with an astringent lotion. But these remedies are often inferior to a strong tincture of Thuja occidentalis, applied to the part three times a day for a week or a fortnight. Sometimes the warts fall off in two or three days after this application, leaving the base perfectly healed. Five drops of the tincture should be taken in a wine-glass of water internally every night and morning during the period of the external application.

Condylomata about the anus or pudenda of either sex - whether of a syphilitic character or otherwise - are often rapidly cured by the external application of the same tincture. (Learning1 has found Thuja of service in warts, epithelioma, and in bronchial affections. Personally we have employed it for many years, and with the utmost satisfaction in non-syphilitic warts of the penis and vulva (condylomata acuminata). In syphilitic lesions (condylomata lata), however, we have never seen the slightest benefit from its use. In papillomatous growths in general it will be found valuable, as well as in gleet dependent on granular urethritis, employed internally and by injection.

Preparations And Dose. - None officinal. The tincture or fluid extract should be made from the fresh leaves. We have found preparations from the dry plant very unsatisfactory. Our own experience has been confined to doses not exceeding fifteen minims, but quite recently a case of cure of supposed epithelioma has been reported in which the dose was a drachm.)

1 N. T. Jour, of Med., 1855.