This section is from the book "Materia Medica And Therapeutics - Vegetable Kingdom", by Charles D. F. Phillips. Also available from Amazon: Materia Medica And Therapeutics: Vegetable Kingdom.
Active Ingredients. - Kino is inodorous, but has a very astringent taste, which ultimately becomes sweetish. Artificial heat does not affect it, but in the mouth it softens readily, turning the saliva blood-red, and when chewed, clinging to the teeth. In cold water it is partially soluble, in boiling water more so; and in alcohol it is largely or almost entirely soluble. The constituents are a peculiar kind of tannin, called mimo-tannic acid (or Catechu-tannic acid), C13H12O5, and another astringent principle, called Catechine, probably isomeric with Catechu-tannic acid (described as a constituent also of Pale Catechu), with some red gum, and other unimportant ingredients.
Physiological Action. - Kino operates in the same manner as catechu, but the action is frequently less powerful, kino being less soluble than catechu, when taken into the system.
Therapeutic Action. - Kino was introduced into the Edinburgh pharmacopoeia in 1774, and into the London one in 1787. It is chiefly employed in obstinate chronic diarrhoea, and then often in combination with chalk or opium. It has, likewise, been found useful in leucorrhoea, and as a tonic in intermittents. As a topical astringent, it possesses a degree of value, and also for employment as a gargle.
Preparations and Dose. - Kino, gr. v.-xx. (.30 - 1.25); Tinct. Kino, 3 ss. - ij. (2. - 8.); Pulv. Kino, Co. (B. Ph.). gr. v. - xx. (.30 - 1.25).