Some remedies extend their action throughout the whole living sys -tem; others, operating upon one or more of those functions, as the circulatory and nervous, which pervade the body, are apparently felt in all parts of it, though not strictly universal in their direct influence. All these may be denominated general remedies. Another large division act specially on some one part or organ, or, if they affect the general system, do so only indirectly or secondarily. These may be called local remedies; and thus we have the basis of the first subdivision.