When an injury has broken down and destroyed cell-life--when inflammation from any cause has broken down and destroyed cell-life--reparation cannot be perfect. The destroyed cells will be supplanted by sclerose tissue. This scar, or cicatrix, is more or less of a menace to the health and life of the tissue in which it is located, depending, of course, on the vital importance of the organ or tissue. If of the valves of the heart, the ending will be fatal without a rational treatment begun in time; if of the neck of the womb, a cancer may be the ending, if proper treatment is not instituted in time; if a gland of the breast be the injured part, then, without proper treatment, cancer will end all; if a stricture of the urethra, and neglected, bladder, and possibly kidney, disease may be the consequence; if a catarrhal thickening of the mucous membrance of the bile duct, and its obstruction is not relieved, stone in the gall bladder will result; if the hardening is of the spinal cord, ataxia and other forms of paralysis may result. The affections that result from hardening can only end with those limitations of tissues and organs of the body; and offenses to the tissues and organs of the body which may cause cicatrical tissue end only with the sum of everything in the environment of man capable of injuring his body and mind.

The lower the order of tissue life, the more power it has for regenerating. In a few animals it is possible to remove a portion of the liver, spleen, or kidney, and it will be rebuilt. It is said that the mutilated organs are reproduced according to their normal type. In spite of this fact, their lives are short compared with that of man, who has a very limited power of reproduction.