In 1898, Guenther Enderlein (1872-1968) graduated with honors in natural sciences, physics and zoology from Leipzig University, and in 1914 he became a bacteriologist and serologist at the German military hospital at Stettin. Enderlein had studied the findings of Antoine Bechamp and had further studied under Rudolph Leuckart, the zoologist who initiated the modern science of parasitology, and also under Otto Schmidt, the doctor who in 1901 reported the discovery of parasites in the blood of cancer patients. (Schmidt was not the first to discover cancer parasites. As early as 1890 Scottish pathologist William Russell reported on widely variegated microbes present in all cancer tissue, which microbes were referred to as "Russell bodies".)

It was in 1916 while studying typhus that Dr Enderlein observed microscopic living entities in blood samples which he called protits, which could move, unite with other microorganisms and disappear. Later on, using dark field microscopy, he observed that these micro-organisms could change in form through a cycle of countless variations, and he also described how different types of protein-based micro-organisms flourished in blood cells and plasma of all animals, representing an essential part of the normal life process. As part of the normal life process, these microorganisms live together within the body in a mutually beneficial relationship known as symbiosis. However, he noted that with any deterioration of the body's interior environment in which the pH of the blood becomes either acid or strongly alkaline* the normally harmless microbes would begin to change and in stages evolve into forms of a pathogenic nature, just as Bechamp had said. Enderlein recorded these observations in his book Bakterien Cyclogenic (The Life Cycle of Bacteria), published in 1925 (translated from the German by Dr Phillip Hadley), at which time he became a member of the Microbiological Society of Vienna of which he was later to become president.

*Cholera is a disease characterized by the onset of diarrhoea and occurs in different degrees from mild to fatal; the etiology of the mild forms is uncertain in the presence of varying kinds of bacilli (germs) but Asiatic or true cholera is transmitted by a bacillus called Vibrio cholera, a member of a large group of gram-negative, comma-shaped bacteria that are morphologically indistinguishable from one another. Some of these bacteria appear normally and symbiotically in the body and are often found associated with mild diarrhoea. However, true cholera can be transmitted by a germ different to Vibrio cholera called El Tor vibrio which, unlike Vibrio cholera, can be found in the absence of disease as well. Another fact about the cholera germ which further supports Dr Enderlein's thesis is that it thrives best in a strongly alkaline milieu.

Dr Enderlein's sixty years of research using more refined equipment achieved discoveries which precisely duplicated those of Bechamp and confirmed Bechamp's views. Enderlein found that:

  1. The cell does not represent the primary living unit of the body. Instead the primary units were tiny biological units which he called protits which live within the cells.
  2. The blood is not sterile, but contains micro-organisms capable of causing mischief given the proper milieu.
  3. Certain micro-organisms undergo an exact, scientifically verifiable growth cycle.

Presently Dr Enderlein's findings continue to be confirmed by Dr Erik Enby of Gothenburg, Sweden, where he practises biological medicine and is assistant physician at the Vasa Hospital. Dr Enby's observations of microorganisms are done using interference contrasting microscopy.

Shortly after Bakterien Cyclogenic was published, American researchers F. Loenis and N.R. Smith collaborated to write Studies of the Life Cycles of Bacteria, which Enderlein welcomed as sufficient support to finally finish the pleomorphism vs monomorphism argument, but as always the orthodox medical establishment was not interested in anything which did not agree with the textbooks and the monomorphic dogma contained therein. Another "medical heretic" was Dr William F. Koch, BA MA Ph.D MD,* of Detroit, whose life's work was the study of the biochemistry in disease. In his book The survival factor in neoplastic and viral diseases: an introduction to carbony (1961) he says:

"Glover showed in 1923 that the cancer virus existed in a pleomorphic form that was a bacillus in one phase and coccus in another, and virus in the third phase. He also showed it could exist in a fungus or mycelium phase. The latter form has been identified lately by Irene Diller and some others, and the whole chain of forms was independently proved by von Brehmer in the last few decades as well. The work was thoroughly repeated and proved by my friend Jacob Engel and George Clark, at the US PHS Laboratories but, for reasons we will not discuss, they were not allowed to publish their findings."

*See Chapter 12: Heart Disease: Civilization's No. 1 Killer.