Guadalupe , a river of Texas, rising in Edwards co., in the S. W. part of the state. It flows nearly E. until it enters the alluvial plain that stretches toward the gulf of Mexico, from which point it pursues a general S. course to its junction with the San Antonio, about 12 m. from its mouth in Espiritu Santo bay. Its length is about 250 m. On its banks are the towns of New Braunfels, Seguin, Gonzales, Clinton, and Victoria. The San Marcos, which enters the Guadalupe in Gonzales co. from the north, is the principal tributary. Steamers have occasionally ascended to Victoria.

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Guadalupe , a central county of Texas, drained by the Guadalupe river; area, 807 sq. m.; pop. in 1870, 7,282, of whom 2,534 were colored. It has an undulating surface, covered with prairies and good timber. The chief productions in 1870 were 197,889 bushels of Indian corn, 13,556 of sweet potatoes, and 2,874 bales of cotton. There were 6,859 horses, 6,061 milch cows, 51,454 other cattle, 3,262 sheep, and 11,748 swine. Capital, Seguin.