Nice, Or NicaeA (Now Isnik), an ancient city of Asia Minor, in Bithynia, situated on the E. shore of Lake Ascania, 54 m.-S. E. of Byzantium or Constantinople. It was said to have been colonized by Bottia?ans, who called it An-core, and having been destroyed by the Mysi-ans was rebuilt after the death of Alexander the Great by Antigonus, who named it Anti-gonrea. Lysimachus changed this appellation to Nicrea in honor of his wife. It became a place of great importance, and disputed with Nicomedia the title of metropolis of Bithynia. Under the Byzantine emperors it was long a bulwark against the Arabs and Seljuks, the latter of whom conquered it about 1080. Before the end of the century it was taken from them by the soldiers of the first crusade, but it was restored at the next treaty of peace. In 1204, Constantinople having become the seat of a Latin empire, Theodore Lascaris made Nicaea the capital of a Greek kingdom or empire in western Asia, comprehending Bithynia, Mysia, Ionia, and a part of Lydia. He was succeeded by John Ducas Vatatzes (1222-,55), Theodore II. (1255-9), John Lascaris (1259), and Michael Palaeologus, who in 1261 transferred the seat of power to Constantinople. In 1330 the city surrendered to Orkhan, and was incorporated with the recently founded Ottoman empire.

The modern town is a place of no importance, comprising fewer than 200 houses and about 1,000 inhabitants.