Mortification, or Sphacelus, in the animal economy, is generally defined to be a total extinction of the natural heat of the body, or rather of a particular part; in consequence of inflammation.

Under the article Gangrene, we have already given some hints respecting the nature and treatment of this dangerous affection, so that we shall at present only add a few supplementary observations.

Mortifications of the external parts, such as the legs and feet, more frequently occur in debilitated persons, and those who are addicted to the use of spirituous liquors; or in the aged; gouty, scorbutic, etc. than in the young and robust.

Beside the means suggested for the removal of this complaint, vol. ii. p. 361-2, these are three other remedies, which have fre-quently proved successful

Carminati recommends the external application of the.gastric juice of animals to the parts affect-ed, in a manner similar to that described vol. i. pp. 429-30.

The late Mr. Pott, after having experienced the inefficacy of the Peruvian bark in the cure of mortifications, accidentally discovered that opium, taken in pretty large doses (one grain every three or four hours), first procured a remission from the great and continual pain which the patient felt in his foot and ancle; and then stopped the progress of the disease-; but Mr' Pott carefully watched the narcotic effects of this drug; keeping the body open by laxative injections; Thus, the mortified parts were cast pff, the bones separated, and a clean sore was produced : while this was healing,the dose of the opiate was gradually diminished, and at length totally relinquished-.

The last, and probably most effectual, remedy against this fatal disorder, appears to be the application of fixed air, whether by means of filling, large Madders, or other vessels, in which tie affected limb may be confined; or by the repeated use of fermenting poultices.— In the 3d vol. of the London Medical Transactions,Mr. John Power communicates a case, in which all the toes had perished, and the mid-die of the foot had mortified; but a cataplasm of wheat flour and honey, fermented by the addition of yeast, completely stopped the progress ; healed the sore; and the patient, aged 67, recovered her health and spirits.