Acetanilidum
Description
This section is from the book "Laboratory Manual Of Pharmacology", by A. D. Bush. Also available from Amazon: Laboratory manual of pharmacology.
Acetanilidum
Acetanilid is made by treating aniline with glacial acetic acid in the presence of heat, with purification of the residue by sublimation and recrystallization.
Properties:
Form ................................ | Solubility: |
Feel ................................. | Hot H2O ....................................................................................... |
Color .................................. | Cold H2O .................................................................................... |
Odor .................................... | C2H5OH ....................................................................................... |
Taste ................................................ |
Tests showing some incompatibilities:
Triturate with Resorcinol ...................................... | Con. KOH ................................................................................................ |
Con. HNO3 .......................................................... | Tinct. Ferri Chloridi ..................................................................... |
Therapeutics. - Acetanilid has had wide use in the past as a sedative and analgesic, being used to lessen the pains of neuralgia and rheumatism, but it is rather dangerous through its depressant action on the heart; this untoward property also interferes with its utility as an antipyretic. Dose, 0.2 Gm.
Two closely related products are: Acetphenetidinum and Antipyrina. Dose of each, 0.3 Gm.
Properties:
Appearance.......................................................................................... | Appearance........................................................................................ |
Color ......................................................................................................... | Color ......................................................................................................... |
Odor ......................................................................................................... | Odor ......................................................................................................... |
Taste ......................................................................................................... | Taste ....................................................................................................... |
Solubility: | Solubility: |
H2O...................................................................................................... | H2O...................................................................................................... |
C2H5OH ....................................................................................... | C2H5OH...................................................................................... |
Incompatibilities and therapeutic indications similar to Acetanilid; Acetphenetidin is probably less dangerous.
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