- Definition. - The salicylate, 2C20H14N2O2.C7H6O3 + H1O, of the alkaloid quinine.

Description and Properties. - Colorless needles, permanent in air, but acquiring a pinkish tinge after a time. Soluble in cold water (1: 77), somewhat more so in warm (1: 35), in alcohol (1: 11), and in glycerin (I: 16) at 25o C.

It contains 68.79 Per cent, quinine (the bisulphate contains 59.1 per cent. quinine, the hydrobromide 76.6 per cent., the hydrochloride 81.8 per cent., the sulphate 74.3 per cent.). The bisulphate is soluble in 8.5 parts of water, the hydrobromide in 40 parts, the hydrochloride in 18 parts, the sulphate in 720 parts; the official alkaloid (containing 3 molecules of water) is soluble in 1550 parts of water.

Dose. - Average dose: 4 grains (0.250 Gm. = 250 milligrammes), U. S. P.