Cases are on record where the liver has been the seat of cancerous changes, proving the possibility of such an affection invading that organ. The disease in nearly all if not all cases, attacks other parts or organs of the body first, and the changes in the liver are of secondary occurrence.

It has been found circumscribed or confined to certain portions of the organ, and appeared in the form of nodules or tumors varying in size. Sometimes a tumor has been found to occur singly, again the whole liver has been studded with them.

Cancerous deposits take on two varieties which are termed the hard and the soft. With either the liver is usually enlarged, and when the former exists its presence can be more easily determined, the hard tumors being felt. The soft variety can rarely be detected during life.

Cancer of the liver rarely occurs except in very old dogs. If the bulging tumors can be felt, a correct diagnosis might be reached. The general manifestations of the disease are progressive emaciation, debility, abdominal enlargement, and possibly jaundice late in the affection.

Dropsy of the extremities is also liable to occur. Digestion is destroyed and the appetite lost. Diarrhoea usually occurs, and all the signs of ex-haustion are present. Pain may be prominent as a symptom.

Treatment can have no other result than palliation, and possibly the prolongation of life.