The author has endeavored to ascertain what agents are able to destroy the spores of bacilli, how they behave toward the microphytes most easily destroyed, such as the moulds, ferments, and micrococci, and if they suffice at least to arrest the development of these organisms in liquids favorable to their multiplication. His results with phenol, thymol, and salicylic acid have been unfavorable. Sulphurous acid and zinc chloride also failed to destroy all the germs of infection. Chlorine, bromine, and mercuric chloride gave the best results; solutions of mercuric chloride, nitrate, or sulphate diluted to 1 part in 1,000 destroy spores in ten minutes.--R. Koch.