By S.S. BRADFORD, Ph.G.

Having had occasion during the last six years to manufacture lead plaster in considerable quantities, it occurred to me that cotton seed oil might be used instead of olive oil, at less expense, and with as good results. The making of this plaster with cotton seed oil has been questioned, as, according to some authorities, the product is not of good consistence, and is apt to be soft, sticky, and dark colored; but in my experience such is not the case. If the U. S. P. process is followed in making this plaster, substituting for the olive oil cotton seed oil, and instead of one half-pint of boiling water one and one-half pint are added, the product obtained will be equally as good as that from olive oil. My results with this oil in making lead plaster led me to try it in making the different liniments of the Pharmacopoeia, with the following results:

Linimentum Ammoniae

This liniment, made with cotton seed oil, is of much better consistency than when made with olive oil. It is not so thick, will pour easily out of the bottle, and if the ammonia used is of proper strength, will make a perfect liniment.

Linimentum Calcis

Cotton seed oil is not at all adapted to making this liniment. It does not readily saponify, separates quickly, and it is almost impossible to unite when separated.

Linimentum Camphorae

Cotton seed oil is far superior to olive oil in making this liniment, it being a much better solvent of camphor. It has not that disagreeable odor so commonly found in the liniment.

Linimentum Chloroformi

Cotton seed oil being very soluble in chloroform, the liniment made with it leaves nothing to be desired.

Linimentum Plumbi Subacetatis

When liq. plumbi subacet. is mixed with cotton seed oil and allowed to stand for some time the oil assumes a reddish color similar to that of freshly made tincture of myrrh. When the liquor is mixed with olive oil, if the oil be pure, no such change takes place. Noticing this change, it occurred to me that this would be a simple and easy way to detect cotton seed oil when mixed with olive oil. This change usually takes place after standing from twelve to twenty-four hours. It is easily detected in mixtures containing five per cent., or even less, of the oils, and I am convinced, after making numerous experiments with different oils, that it is peculiar to cotton seed oil.--American Journal of Pharmacy.