During fasting the liver is hard at work processing toxins released from fat and other body deposits. The liver still dumps its wastes into the intestines through the bile duct. While eating normally, bile, which contains highly toxic substances, is passed through the intestines and is eliminated before too much is reabsorbed. (It is the bile that usually makes the fecal matter so dark in color.) However, reduction of food bulk reduces or completely eliminates peristalsis, thus allowing intestinal contents to sit for extended periods. And the toxins in the bile are readsorbed, forming a continuous loop, further burdening the liver.

The mucus membranes lining the colon constantly secrete lubricants to ease fecal matter through smoothly. This secretion does not stop during fasting; in fact, it may increase because intestinal mucus often becomes a secondary route of elimination. Allowed to remain in the bowel, toxic mucus is an irritant while the toxins in it may be reabsorbed, forming yet another closed loop and further burdening the liver.

Daily enemas or colonics administered during fasting or while on cleansing diets effectively remove old fecal material stored in the colon and immediately ease the livers load, immediately relieve discomfort by allowing the liver's efforts to further detoxify the blood, and speed healing. Fasters cleansing on juice or raw food should administer two or three enemas in short succession every day for the first three days to get a good start on the cleansing process, and then every other day or at very minimum, every few days. Enemas or colonics should also be taken whenever symptoms become uncomfortable, regardless of whether you have already cleaned the colon that day or not. Once the faster has experienced the relief from symptoms that usually comes from an enema they become more than willing to repeat this mildly unpleasant experience.

Occasionally enemas, by filling the colon and making it press on the liver, induce discharges of highly toxic bile that may cause temporary nausea. Despite the induced nausea it is still far better to continue with colonics because of the great relief experienced after the treatment. If nausea exists or persists during colon cleansing, consider trying slight modifications such as less or no massage of the colon in the area of the gall bladder (abdominal area close to the bottom of the right rib cage), and putting slightly less water in the colon when filling it up. It also helps to make sure that the stomach is empty of any fluid for one hour prior to the colonic. Resume drinking after the colonic sessions is completed. If you are one of these rare people who 'toss their bile', just keep a plastic bucket handy and some water to rinse out the mouth after, and carry on as usual.