Ampules

Liquid dilution for injection

Active ingredient:

thiamine hydrochloride (vitamin B1), pyridoxine hydrochloride (vitamin B6)

Composition:

1 ampule of 2 ml contains: Medically active substances: 10 mg thiamine hydrochloride (vitamin B1), 5 mg pyridoxine hydrochloride (vitamin B6). Other constituents: 20 mg benzyl alcohol as preservative.

Indications:

neuritis, neuralgia, trigeminal neuralgia, ischialgia, cervical syndrome, herpes zoster, radiculoneuritis because of degenerative spondylopathy.

Characteristics:

Vitamin B1 (thiamine) in its active form, thiamine pyrophosphate (TPP) plays a crucial role in the carbohydrate metabolism. The daily requirement of vitamin B1 depends on the kind of nutrition consumed. If one consumes mainly carbohydrates the need of vitamin B1 increases. Pure vitamin B1 deficiency causes reduced mental and physical power, lack of appetite and muscular atrophie, particularly on the lower extremities. Vitamin B6 occurs in all living cells. The effective compound is pyridoxal-5-phosphate which is an indispensable coenzyme in the amino acid metabolism. In case of a high protein-rich nutrition the need of vitamin B6 is increased, also during pregnancy and in case of hyperthyroidism. A vitamin B6 deficiency can result in particular forms of anaemia as well as in skin diseases.

Application:

Vitamin B Komplex Sanum N injection solution has to be injected slowly i.v. or i.m. Unless not otherwise prescribed for initial treatment during the first days of therapy intramuscular injection with daily 1 ampule of 2 ml, after beginning of recovery 2-3 x weekly 1 ampule.

Side effects:

In singular cases hypersensitivity reactions with skin reactions, urticaria and states of shock particularly allergic predisposed patients may appear. Hypersensitivity through benzyl alcohol appears rarely.

Contra Indications:

In case of suspected vitamin B1 hypersensitivity Vitamin B Komplex Sanum N must not be used.

Advice:

Through the contents of benzyl alcohol Vitamin B Komplex Sanum N must not be used for new-born infants particularly not in case of undeveloped premature babies.

Interactions with other remedies:

Vitamin B1 is broken down in sulphite containing infusion solutions. High dosages of vitamin B6 can weaken the effect of L-Dopa. In case of simultaneous use of isoniazid (INH), d-penicillamin and cycloserine the effectiveness of vitamin B6 can be lowered.

How supplied:

2 ml ampules 10 and 50