As the fever progresses, a typhus abdominalis becomes more and more marked; the evening chilliness, which is followed in bed by several hours' dry heat and thirst, cutting as with knives in the abdomen, and diarrhoea, disappears entirely and is changed to a continuous heat with violent delirium, pains in the limbs, excessive weakness, dry, blackish tongue and lips, burning-red cheeks, subsultus tendinum, floccilegium, sopor with muttering and snoring, small accelerated pulse. When the delirium abates, the greatest anguish is depicted in the features, which takes place more frequently before than after midnight, and is accompanied with prostration of strength. If the patient should be on the point of falling asleep again, he is constantly prevented from so doing by starting as in affright. The following are some of the accompanying symptoms: Redness and lachryma-tion of the eyes, which are no longer susceptible of any impression from without, dryness of the nose, collapse of countenance, fetid odour from the mouth, involuntary discharge of stool and urine; the urine is whitish and turbid during emission, before any colliquative symptoms had set in, and becomes much more so by standing; oppression of the chest is a characteristic symptom for Rhus; this oppression continues from the commencement to the end of the disease, whether terminating in death or recovery.

Rhus is one of the most distinguished remedies both in the commencement and the progress of the disease, in typhus versatilis as well as in stupidus (especially in the latter); it is likewise of great value during the stage of convalescence, when the improvement is very slow, the pulse continues feverish, there is an appetite, but more for particular things, than for natural simple food; there is yet some inclination to diarrhoea, and the oppression of the chest is not entirely removed.

Next to Rhus is Phosphorus, which is principally indicated, when typhus arises from onanism or from a slight cold. This kind of typhus has a long precursory stage, commencing with rheumatic pains in the upper and lower limbs, and accompanied by a capricious sensitiveness; those pains are generally very intense early in the morning and evening, in bed, they increase when a current of cool air comes in contact with the limb, and are frequently accompanied by other symptoms, such as: rheumatic drawing in the nape of the neck, stiffness of the affected limbs, toothache, weariness, and a bruised feeling in all the limbs, vascular erethism with dulness and tightness of the head, palpitation of the heart, stitches in the pit of the stomach, cutting pain in the bowels, and a general sick feeling. If these symptoms should continue for any length of time without any change for the better being effected by the medicine, the disease reaches a higher degree characterized by the following symptoms:

The continuous heat is accompanied by a small, hard, quick pulse, throbbing of the carotids, profuse night-sweats; the sleep is interrupted by shrieks, constant fancies, moaning, tossing about, want of breath, stitches, rattling in the chest, oppressive cough with bloody expectoration (pneumo-typhus); upon waking the patient complains of great heat, dry mouth with thirst, painfullness of every part of the body. These symptoms are accompanied with sensitiveness and rumbling in the coecal region, especially when making pressure upon it, burning feeling in the abdomen and anus, frequently accompanied by half liquid, bloody stools; vertigo with stoppage of the head; the stupefaction and beating pains in the head are very great, there is a gauze before the eyes, hardness of hearing, frequent discharge of blood from the nose when blowing it, and heat in the face. The tongue and lips are dry and parched; the appetite is entirely wanting; the patient, when conscious, complains of bitter taste. (Phosphorus is frequently indicated when the patient lies in a state of stupor.) The urinary discharges are copious, at times depositing a reddish, at times a white flocculent sediment.

A striking symptom is the excitation of the sexual organs, which occurs in both sexes, and frequently increases to satyriasis and nymphomania.

Phosphoric acid is closely related to Phosphorus, but more so to Pulsatilla. Phosphorus may, under certain circumstances, be employed against any form of typhus; Phosphoric acid has a more limited, but at the same time more definite sphere of activity. Even the precursory symptoms of a- phosphoric acid typhus are so well marked that there can be no doubt as to the selection of the remedy. The symptoms are frequently occasioned by long grief, chagrin, care, and increase to such an extent that they become dangerous to life. The precursory stage almost always commences with a gastric derangement, which is even characterized by the peculiar eruption about the mouth; there is a striking rising of air, with nausea, which compels him to lie down, and then frequently increases to a considerable vomiting, with extreme sensitiveness of the stomach and pit of the stomach, which increases more and more as the vomiting continues, and extends over the whole abdomen. The appetite is entirely wanting, the thirst is great, the patient has a particular desire for acid, juicy drinks. Diarrhoea supervenes with borborygmi in the distended abdomen; the frequent light-yellow stools require more particularly the exhibition of Phosphoric acid. If these symptoms be accompanied by intense pain in the inmost parts of the lower abdomen, which is even aggravated by the contact of the shirt; if a red miliary eruption make its appearance in various parts; if the pulse be frequent, weak, sometimes intermittent; if the patient be unable to collect his senses; if muttering delirium, stupor, burning heat of the skin, a dry, parched state of the buccal cavity, and permanency of the recumbent posture be present, frequent doses of acidumphosphoricum will effect the desired improvement. This remedy is always most suitable in the commencement, as well as in the progress of a typhus stupidus, whether this arise from a gastric or erethic typhus: characteristic indications for Phosphoric acid are bland delirium, or silent and quiet recumbent posture, the patient giving a proper answer for a few moments, but shortly afterwards relapsing again into his former condition.