B. Applied to the scalp, caused a papular eruption on the face, Farqu-harson, 116, 1/79, 223.

D. Trichophytosis, chromophytosis, Fayrer, 146, 2/74, 470; Lima, 146, Mar. 6, '75; Smith, 124 79, 193. Psoriasis, Squire, 116, Dec. 23, '76; Stansbury, 110, 4: 297; Benozzi, 131, '78, 231; and many others.

Remarks - It is barely six years since this drug was fairly brought to the notice of European physicians as a parasiticide of remarkable energy. Later Squire, of London, discovered its efficacy in psoriasis. In parasitic affections of vegetable origin it has been found exceedingly useful when they are purely superficial, as in chromophytosis and trichophytosis corporis. On the other band, when the hair follicle is deeply invaded by the fungus, as in trichophytosis capitis or barbie, it has in my experience proved ineffective. In psoriasis, however, it has justly earned a high reputation, and is unquestionably the most efficient external agent we now possess for the removal of this affection. Although somewhat irritant it may be freely applied to the general surface, but should be used sparingly and with caution to the face. This substance is strictly speaking not an acid, but a neutral body, for which the more appropriate name of chrysophan has been proposed. Like many other bodies of this nature it is exceedingly insoluble, dissolving in small propor-tion only in alcohol, ether, and petroleum derivatives. It is usually employed in the form of ointment, containing from 5 per cent. to 15 per cent. of chrysophan.

* Rousseau - Contribution a l'etude de l'acide chromique, etc. Paris, 1878.