I am not in possession of any facts concerning the use of this drug in Leprosy, other than the one mentioned on page 77. The drug, however, is of special interest in connection with the next, the active principle of which also appears to be strychnia. Hoang-Nan. - This drug reaches commerce, or at least reached me in the form of a brownish woody powder, with an intensely bitter taste like that of nux vomica. Physiological experiments have shown that it is a tetanizing drug, and botanical authority refers it to the Strychnos family. A number of writers testify to its utility in Leprosy. The drug is given alone, or in one of the following combinations:

Alum......................................... 1 part.

Native Realgar................................ 2 parts.

Hoang-Nan................................... 2 parts.

or,

Alum........................................ 1 part.

Realgar...................................... 1 part.

Hoang-Nan................................... 2 parts.

These mixtures are made into three-grain pills, of which the commencing dose is one pill daily, to be gradually increased.