Weir Mitchell's treatment for neurasthenia and disorders of malnutrition, independent of organic disease, depends on isolation, massage and overfeeding. The isolation and the moral effect which can be exerted on the patient, to stimulate the will power, are the main factors. A liberal diet is given consisting of milk 3-4 pints, meat 1/2-3/4 pounds, eggs 4-6, bread, potatoes, sweets, vegetables and butter; enough to yield protein 150-200 grammes, fat 75-100 grammes, carbo-hydrates 400-500 grammes, and calories 3,500-4,500.