The Four Horsemen of the Apocalypse represented the four great and dire calamities which should attack the human race, the last of which was death.

To every man, woman and child there appear these four horsemen, and they are lurking just around the corner almost from the moment of birth.

The four great calamities, from the standpoint of the individual, are fatigue, disease, old age and death, and if we live out our time they come to us in about this order, though too often death steps out of line to attack us early in life, from accidents or sudden means of interruption to the usual cycle.

How does it come that these four things, not so very closely related always in thought, should come to be regarded as the four horsemen?

Remember again what Dr. Crile said, that every death from so-called natural causes is merely the end point of a progressive acid saturation, then the connection is plain.

A progressive acid saturation, if really progressive, must have had a beginning somewhere, sometime, and there must surely be some indication of such beginning.

The very first morning that you get out of bed and do not feel impelled to kick the ceiling, that morning you are showing the effects of acid accumulation--the trouble has started, for fatigue is the first stage of this progressive acid saturation.

What is fatigure, anyway? We see more fatigue, we hear about more fatigue, than anything else.

Every one seems to be tired, yawning, stretching, leaning, sprawling, trying to ease the sense of fatigue that is so depressing. ft you try to find out why the tired one is weary you may have difficulty in locating anything that should have caused such a world weariness, and usually the tired one himself can give you very little help on this subject. He is just naturally tired, even willing to admit that he was born tired.

If one has done nothing out of the ordinary to use up energy, if he has slept the regulation period, there is then but one reason for this extreme fatigue that is almost a national handicap, and that is that "drainage is deficient."

More waste has been created, is being created, than can be fully eliminated, and you will remember that Sir William Arbuthnot Lane says that after all there is but this one disease.

Well, this is the first stage of acidosis, toxaemia, acid autotoxicosis, whatever you wish to call it, for it is always only the same thing, acid end-products of digestion created and not eliminated.

So, when you get up in the morning, if you do not feel like kicking the ceiling, then you have started the accumulation of acid end-products of disease that introduce you to the first of the four horsemen, and the other three wait just around the corner.

Have you ever stopped to consider the cost of fatigue?

What is its personal cost to you, what does it cost this great nation, considering that fatigue is well-nigh universal?

This is what it cost one man, before he found out why he was continually tired.

He was a trader in the grain pit, and he told me that day after day he sat down in a big easy chair and let trades, that were easy money for him, go over his head. It was too much trouble to get up from his chair and bid.

He said that not infrequently he has done this when he knew there were several thousand dollars of clear profit in the deal for him, but he was too tired to get up, so he lost this much money in a moment.

This same man fell sick, very sick, hovering for a time on the slippery brink of the grave, yet pulled through, but during his rather long illness his stomach obstinately refused nourishment of every sort, with the result that after four weeks he was fairly well cleaned out, made a nice recovery, went back to the grain pit, and now nothing goes over his head.

The thousands of dollars that he formerly saw floating by, but was too tired to grasp, are now his, because he is not tired any more, and he sees everything that goes on about him.

That is what fatigue does for us, it robs us of opportunity in everything because we are tired and we lose interest.

One business man in Buffalo doubled his income in three months after he learned how to eat, because his income depended on just how he handled his office force every day, and as he was tired and his head was confused he handled them very poorly, so his income was not what it should have been.

His little wife was dieting, even though she was already very thin, but after changing her manner of eating she realised that she felt better, her head ached less, she was less tired, and so she kept on dieting, even though her husband, a big fat fellow, ridiculed her continually for dieting when already too thin, his idea evidently being that when one diets it is always because one is too fat.

In a few weeks this little lady let her maid go, something she had never done without before in her whole married life, and she got the meals, thus getting a good chance to improve her husband's condition and his temper.

In three months this husband's income had doubled, he was pleas' ant and cheerful about the house, he was an enthusiastic follower of diet, and he knew then why he had before been irritable and tired and unsuccessful in his business, and you could not dog him away from his changed habits of eating, for he realized that on these depended wholly his great improvement in condition.

Now why did this man feel that he was unsuccessful before, and why does he know now that he can be as successful as he wishes to be?

The cause before was the presence of this first of the four horsemen, fatigue, the constant accompaniment of failures in everything, and his come-back is due wholly to the fact that he has learned that all his former fatigue was from eating wrong foods, or wrong combinations of right foods, a thing he would not voluntarily go back to for a large sum of money.