Goldberger and fifteen of his associates next tried in a number of ways to transmit pellagra to themselves by a series of innoculations with blood, nasopharyngeal secretions, feces, urine and desquamating epithelium. The results of this heroic experiment were entirely negative. Not a single one of the volunteers showed any evidence of the disease. These subjects were all presumably nourished on a satisfactory diet previous to and during the experiment, and this could be interpreted as evidence in support of the view that pellagra is a disease of low virulence, and that it is liable to attack only that portion of the population which, for one reason or another, has suffered a lowering of resistance (15).