Cubebs, the berries of piper cubeba, a plant growing wild in Java, Penang, and probably other parts of the East Indies. The berries are hard, round, blackish, stalked, and veined, with an aromatic taste and smell. They contain a volatile oil and a hard and soft resin. The latter may be regarded as cubebic acid, and seems to be the active medicinal constituent. It passes into the urine and imparts to it a peculiar odor, when taken in doses of 10 grains every two hours; in larger doses it increases the quantity of the urine and causes irritation of the urinary passages. Cubebs modify the secretions of all the mucous membranes, but act especially on those of the urinary passages. They are accordingly used in the treatment of those membranes. The diseases in which they are commonly employed are gonorrhoea, gleet, leucorrhcea, chronic inflammation of the bladder, and chronic bronchitis. When the latter affection is attended with profuse expectoration and debility, the administration of cubebs is often followed by the happiest results. Acute inflammation of the mucous membrane, whether bronchial or urinary, contraindicates the use of cubebs. They may bo administered in the forms of powder, oleo-resin, which is another name for the fluid extract of cubebs, oil, and tincture.

One to three drachms of the powder may be given three times a day. The dose of the fluid extract is from a few drops to a drachm; of the oil, 10 or 12 drops: of the tincture, from half a drachm to one or two drachms. All of these preparations are most agreeably taken when mixed with some thick sirup or mucilage. Cubebs enter into many of the bronchial lozenges or troches that are sold for the relief of bronchitis, coughs, etc.

Piper cubeba.

Piper cubeba.