4578. Class No

4578. Class No. 5, of Classified Fluid Extracts. The extracts obtained by this process are termed acetic fluid extracts. The acetic acid is introduced to control the tendency to decomposition, caused by the existence, in the drugs treated in this manner, of a salt consisting of an alkaloid and an organic acid. The fluid used is a mixture of J fluid ounce acetic acid and 3 pints diluted alcohol; and the drugs should be reduced to a No. 60 powder.

Ergot. Lobelia Leaves. Hemlock (Conium).

Moisten 16 troy ounces of the powder with 1/2 pint of the acetic mixture; pack it in a conical percolator, and displace 3 pints, reserving the first 12 fluid ounces, using dilute alcohol during the last part of the percolation. Evaporate the latter percolate to 4 fluid ounces, at a temperature not exceeding 150° Fahr.; mix this with the reserved tincture, and filter through paper.

4579. Class No

4579. Class No. 6, of Classified Fluid Extracts. Under this division are placed oleoresinous fluid extracts. (See No. 4573 (Procter's Classified Formula for Making Fluid Extracts).) The menstruum employed is deodorized alcohol, and the drugs are used in No. 50 powder; except canella, Ceylon cinnamon, elecampane, and orris root, used in No. 60, and myrrh in No. 30 powder.

Capsicum.

Orris Root, (Iris Floren-

Canella.

tina).

Cardamom.

Myrrh.

Cloves (Caryophyllum).

Pellitory Root (Pyreth-

Ceylon Cinnamon.

rum).

Cubebs.

Allspice (Pimento).

Elecampane (Inula).

Prickly Ash Bark (Xan-

Lupulin.

thoxylum).

The oleoresin of the above substances are to be obtained by percolation, and distilling off the alcohol.

This process of obtaining the oleoresins was modified before adoption in the U. S. Ph, by substituting ether for deodorized alcohol as the menstruum employed. The five following oleoresins are officinal preparations.

4580. Oleoresin of Capsicum

4580.    Oleoresin of Capsicum. Take 12 troy ounces capsicum in fine powder, press it firmly in a cylindrical percolator, and gradually pour ether on it sufficient to displace 24 fluid ounces. Recover from this, by distillation on a water-bath, 18 fluid ounces of ether, and expose the residue in a capsule until the remaining ether has evaporated; lastly, remove, by straining, the fatty matter which separates on standing, and keep the oleoresin in a well stopped bottle. ( U. S. Ph).

4581. Oleoresin of Cubebs

4581.    Oleoresin of Cubebs. Moderately press 12 troy ounces cubebs in fine powder into a cylindrical percolator, and treat by the same process as the capsicum in the last formula. (U. S. Ph).