"Fleming has well said that it is a great and dangerous error to suppose that the disease commences with signs of raging madness, and that the earliest phase of the malady is ushered in with fury and destruction. The symptoms appear very gradually, and at first there is only the slightest evidence of brain disease. The animal's habits and behavior are changed. It may be more restless and affectionate than usual, seeking to be near its master or mistress, fawning, licking the hands or face", and apparently seeking for sympathy or assistance. Such caresses are, however, extremely dangerous, for the animal's tongue, moist with virulent saliva, coming in contact with a part where the skin is thin, abraded, or wounded, may fatally infect the person with whom it is endeavoring to demonstrate its affection. The smallest abrasion may be, as Bouley has impressively said, a door opened to death; and such a death! The instances in which hydrophobia has developed from such inoculations are very numerous, and everyone should be warned against this kiss of affection, which carries with it not only death, but sufferings which are far more to be dreaded than the fatal . termination.

• "In most cases dogs first become dull, gloomy, morose, taciturn, seeking solitude and isolation in out-of -the-way places, or retiring under pieces of furniture. But in this retirement they can not rest; they are uneasy and agitated; they lie down and assume the attitude of repose, but in a few minutes are up again, walking hither and thither, 'seeking rest, but finding none.' Occasionally this restlessness may disappear for a time, and the animal become lively and affectionate; oftener it sinks into a sullen gloominess, from which even its master's voice rouses it but temporarily. It becomes more and more desperate in its efforts to prepare a comfortable bed, pawing or scattering the straw, or, if in a house, scratching, tumbling and tearing cushions, rugs, curtains, carpets and everything of that kind within its reach.

"At this period dogs may have aberrations of the senses, of the sight, hearing, and feeling, which cause hallucinations and lead them to think that they are being annoyed by something, or that some animal or person is endeavoring to injure them. They crouch, ready to spring upon an enemy; they rush forward and snap at the air; they throw theselves, howling and furious, against a wall, as though they heard sounds beyond it.

"While at first the affected dog may not be disposed to bite, it becomes more dangerous as his hallucinations and delirium increase. The voice of the master or of an acquaintance may dispel the aberrations temporarily and lead him to friendly demonstrations, but an unexpected movement or touch may bring on another access and lead to a quick and unexpected bite.

"The disturbance of the sensations leads to chills and itching. If the place where the bite occurred is accessible the dog licks the scar, and later bites and tears the tissues. This tearing of the flesh is not always confined to the site of the inoculation, but certain regions of the body appear to lose their sensitiveness, and at the same time to convey to the brain the sensation of itching. The animal in this case bites into its own flesh with apparent pleasure and satisfaction.

Such animals take food until the disease is considerably advanced, if it is something which can be swallowed without mastication; otherwise it is dropped after remaining a short time in the mouth.

"Difficulty in swallowing is an early symptom, and frequently leads the unsuspecting owner to conclude that the animal has a bone in his throat. A dog which appears to have a bone in his throat is on general principles one of the most dangerous animals in existence. The supposed bone may be there, but on the other hand the symptoms which lead to this supposition may be due to partial paralysis caused by rabies, and the owner may be inoculated with the virulent saliva while thrusting his finger or hand in the dog's mouth to discover a bone which has no existence but in his imagination.

"It is commonly believed that mad clogs have fear of water and are unable to drink, but there could be no greater mistake. In this respect they differ entirely from the human patient. They have no fear or dread of water, but continue to drink until paralysis has progressed so far that they are no longer able to swallow. The fact that a suspected dog is seen to drink or to wade into a stream is consequently no evidence that he is not mad.

"When the furious symptoms come on, the dog leaves his home and goes upon a long chase, with no apparent object in view other than to be traveling onward. He trots at a rapid pace, eye haggard, tail depressed, indifferent to his surroundings. He flies at and bites dogs and persons whom he meets, but usually does not apparently search for them, or even notice them if they remain quiet. Dogs in this condition may travel many miles, and finally drop from exhaustion and die. Often after an absence of a day or two they return to their home, exhausted, emaciated, covered with dust and blood, and presenting a most forlorn and miserable appearance. Those who have pity for such an animal and try to make it clean and comfortable, are in great danger of being bitten, for the disease has advanced to a point where the delirium or insanity is most marked, and where a treacherous bite is most common. Doubtless the clog has no intention of injuring a friend, and would not do so did he net see that friend transformed by his disordered vision into some distorted and unrecognizable shape, which he thinks is about to injure him. Rut while we may give the clog due credit for not intentionally and deliberately inoculating his friends with his fatal virus, let us not forget that the inoculation is no less deadly because it is the result of the abnormal working of a disordered mind. Whatever the sentiment may be which leads the dog to turn upon his master or mistress and inflict an injury, the duty remains the same for the owner to take clue precautions to prevent such an occurrence.