Col. David Bruce who, in Uganda and elsewhere has been inquiring into the cause, effect and distribution of "sleeping sickness, " addressed a meeting at the Royal Institute of Public Health on the subject. Col. Bruce said that in certain parts of the country where the disease had broken out some time between 1896 and 1901 it had in a short time reduced a populous and richly cultivated country to a depopulated wilderness. Sleeping sickness was essentially a disturbance of the functions of the brain. A patient might go about doing his ordinary work for years without his friends noticing that there was anything the matter. But gradually a slight change in his demeanor became evident; he was less inclined to exert himself; he lay about more during the day; and at last his intimates saw that he had the first symptoms of that absolutely fatal disease. His investigations had led him to believe that probably the disease was introduced from the Congo; that it was caused by the entrance into the blood of a protozoal parasite, and that the infection was carried from the sick to the healthy by a species of fly. Where there was no fly there was no sleeping sickness. In other words, they were dealing with a human tsetse fly disease. Sleeping sickness was found to have a very peculiar distribution. It was restricted to the numerous islands that dot the northern part of the Victoria Nyanza and to a narrow belt of country a few miles wide skirting the shores of the lake, but only in localities where there was forest with high trees and dense undergrowth.