The same forms of softening which happen in the brain, are found to occur in the spinal marrow also. But, on the whole, they are more rare in the latter. White softening very seldom reaches that degree of complete destruction of the nervous tissue, which is so frequently met with in the brain, especially in the neighborhood of the ventricles. Red softening (myelitis) assumes the very remarkable form which I have just described as central softening of the cord.

Yellow softening may, without doubt, occur in the cord as a primary and idiopathic disease; but my own observation has furnished me with instances of its secondary form only in and around spots of inflammation, and encompassing morbid growths.

Induration of the cord, though comparatively rare, yet does occur in all the forms, and with all the import which were asserted of it in the brain. Indurations of slight degree are the sequels of general diseases, and are unaccompanied by any manifest further anomaly. More considerable indurations are combined with atrophy. And lastly, condensations and callosities of parts of the cord, are met with as consequences of inflammation, apoplexy, and morbid growths. They are seated mostly in the white columns.