Tubercle occurs primarily as tubercle of the uterine mucous membrane; the uterine parenchyma is like the submucous muscular layers, only attacked secondarily by tubercle.

It generally occurs in the uterine mucous membrane in the shape of an infiltrated mass, which fuses into and attacks the uterine parenchyma to a greater or less extent. The mucous membrane appears converted into a fissured, cheesy, purulent mass of tubercle. The cavity of the uterus contains tubercular pus, which may be retained in consequence of closure of the orifice, and accumulate so as to cause a globular distension of the organ. The disease is very rarely observed in its early stage, in the shape of scattered or grouped gray miliary tubercle of the mucous membrane and the adjoining submucous tissue.

Uterine tubercle is formed during childhood, in the period of puberty, and during the prime and even, though rarely, during the decline of life. It is most frequently complicated with tubercle of the Fallopian mucous membrane, and with the latter may constitute the primary tubercular affection. It is also found complicated with abdominal tubercle, and especially of the abdominal lymphatic glands, and of the peritoneum; and may serve as a point of discharge for the latter. A translation of the tubercular disease to the urinary passages is very rarely observed.

It is curious that the tubercular deposit stops short at the cervix, and very rarely passes even beyond the internal orifice of the womb; the vaginal portion is never affected with tubercular disease. This is extremely remarkable on account of the marked contrast offered by carcinoma, both in reference to its primary and secondary development.