Cretefied Tubercle resides, for the most part, within textures isolated by products of inflammation, entering into a fibroid transformation and then cornifying and shrivelling into a callous capsule. Both together draw down upon themselves the surrounding textures in scar-like corrugations.

Such are the metamorphoses of genuine tubercle of the one and the other form. There occur, however, complicated metamorjihoses corresponding to various combinations of the different tubercle-blastema. Thus:

(a.) The combination of gray with yellow tubercle is frequent. Where, in this combination, the latter passes info softening, the gray tubercle, like textures in contact with tubercle-pus, becomes destroyed. Where the softened yellow tubercle cretefies before this destruction of the gray is effected, the latter cornifies independently; and if it happen to be peripherous to the other it encircles the cretefied tubercle with a sheath of gray cornified tubercle, differing from that callous exudate-capsule which results from inflammation of the surrounding textures.

(b.) Just as tubercle blastemata combine with one another, so, in like manner, does organizable blastema enter occasionally into combination with tubercle. Its existence is of course scarcely demonstrable in yellow tubercle, in the metamorphosis of which it becomes itself destroyed. If cretefaction set in early, it may become organized so as not to be easily distinguished from a subsequently effused blastema, the product of inflammation.

The combination of gray tubercle with organizable fibrin is more susceptible of proof. The instances are not rare in which, hard by pure gray tubercle, granulations are found in which one portion of their blastema is in progress of organization to a fibrous texture, whilst the other abides in its primitive condition, and eventually falls into decadence - cornifies.

There are, indeed, as we shall presently have to show, granular tubercles resulting from inflammation upon serous membranes, - that is, solidifying exudates or granulations as big as poppy-seeds or millet-grains, which in their entirety change into fibroid textures - into areolar tissue. They occur, along with blastemata, consolidated into pseudomembranous areolar tissue, or along with gray tubercle, or even with both gray and yellow, softening tubercle.

The organizing of these granulations consists in the development of a more or less determinate fibrous texture. They acquire the whiteness, the resiliency and elasticity, the fibrous-torn surface, the general characters of little fibrous tumors; or else they change into velvet- or felt-like fasciculi of connective tissue.

They are found upon the peritoneum, especially of the liver and spleen, as also occasionally upon other serous membranes. The Pacchionian granulations upon the arachnoid, the granulations upon the investment of the ventricles of the brain, are upon the whole of the same character.

It is intelligible, from hence, in how far, and in what sense, we are warranted in speaking of a textural conversion, an organization of tubercle, as a metamorphosis of this alien growth. It is intelligible, namely, that growths, whatever resemblance they may bear to tubercle, lose their import as such, in other words, reveal their non-tuberculous character, with the slightest textural conversion.

Intimately connected with the above is the question as to whether tubercle contains bloodvessels of its own? The question may belong rather to a bygone day. It is for the present day, however, to set this point at rest for all time!