The similarity of the crasis in this class of diseases with the typhous and exanthematous crases is very striking. It even partakes, in common with these, of a proneness to localize itself upon the intestinal mucous membrane in the follicular apparatus of the ileum, - in a tumescence [product-formation] of the Peyerian and solitary gland capsules.

To this category belong diseases with obvious anatomical disturbance in the nervous centres, and again diseases in which such disturbance is either wanting or subordinate and consecutive. Such are meningitis, acute hydrocephalus, apoplexy, and the like; and again, acute tonic spasm and convulsions, tetanus, trismus, puerperal convulsions, protracted epileptic convulsions, etc.; lastly, hydrophobia.

In the latter diseases, more especially, in which up to the present day, no anatomical disturbance is demonstrable, the question arises as to whether the nervous system be substantially impaired at all, - whether the anomaly in the crasis be not the primary cause of the nervous phenomena.

It appears to us that, although the most accurate examination may be inadequate to prove any palpable anatomical disturbance, a primitive affection of the nervous system must nevertheless exist, and be that which determines the [secondary] anomaly of the crasis.

This crasis not unfrequently degenerates into putrid decomposition. It often becomes converted into pyaemia, and not unfrequently issues in acute softening.

In fine, those rapidly destructive liquefactions of the blood may be here classified, which, under the name of asphyxia furnish forth the majority of instances of sudden death, commonly through hyperaemia of the lungs with acutely developed pulmonary oedema.