A crasis the existence of which is shown from the exclusive relation stated, in the general section on Tubercle, to exist between cancer and tuberculosis.

To demonstrate a cancer-dyscrasis from anatomico-clinical data is one of the most difficult tasks. The basis of such a demonstration is the immediate character of the blood, the peculiarity of the cancer-formation, and of other exudates brought about in various ways under the crasial influence; and, lastly, their relation to new growths proper to other known crases.

The blood itself affords evidence of a hypinosis. This is, however, not of itself alone cognizable as a specific cancer hypinosis. To prove this the presence of cancer-formations is indispensable, and even these must needs give evidence of their general import, either by redundant-growth or by multiplication; in short, they must in some way betoken a direct relation with a dyscrasial state of the blood.

Further evidence respecting albuminosis is afforded by the presence of albuminuria, of lardaceous infiltration of the liver, spleen, kidneys; more particularly, however, by inflammatory products, as albuminous, white, emulsion-like, in part slowly solidifying, ulcerating, or cancer-forming exudates; lastly, by the exclusion of concurrent fibrinous products, and especially of fibrinous tubercle.

The abundant fat-formation not unfrequently co-existent with carcinoma may be cited in proof of the participation of fat in the cancerous albumen-crasis. This is exemplified in osteo-porosis from the excessive formation of bone-medulla; in the fatty contents of the cancers, and of albumino-cancerous exudates; in the deposition of fat as cholesteatoma, as gall-stone, etc.

The cancerous hypinosis manifests its impress in various grades. It is intense in cases of voluminous, exuberant cancers; in very widely-spread cancer-production, whether spontaneous, or called forth by the extirpation of bulky carcinomata; but most especially in cancer of acute growth, and of the medullary character. The blood often contains, in nucleus-and cell-formations, the elements of cancer. In chronic vegetation, and especially in pure fibrin-cancer, the hypinosis is often less marked; whilst, in cancer of local import, it may be altogether wanting.

The cancer-crasis is either primitive or consecutive, that is, developed out of a hitherto local cancer. It is either acute or [more often] chronic.

The acute crasis is in rare instances protopathic; more commonly, however, it is developed out of the chronic, especially after the extirpation of extensive cancers. It localizes now in the more vigorous growth of a cancer already in existence, now in the simultaneous or in the successive, hasty production of new cancers [of the medullary form] in the most various organs and textures, conducing thus to rapid wasting of the blood, and proving fatal within a term not exceeding that of the most acute crases known.

In its chronic development it terminates in marasm of the blood, in hydremia, in anaemia, the more rapidly, in proportion as the seat of the cancer [in the stomach, for example] is calculated to interfere with the work of nutrition, or in proportion to the loss of blood by hemorrhage.

Under such conditions the cancer-crasis may wear itself out, and the cancer-tumors participate in the waste and decline of the entire organism. This explains the circumstance that in a venosity verging upon hydraemia and depending upon central organic impediments to the circulation, cancers hardly ever occur.

The cancerous hypinosis is, as we have already pointed out, absent in local carcinoma. The concurrent crasis may be the normal, or some anomalous one not of a cancerous nature.