This section is from the book "A Manual Of Pathological Anatomy", by Carl Rokitansky, William Edward Swaine. Also available from Amazon: A Manual of Pathological Anatomy.
An anomalous relation of the blood-corpuscles, founded in dyscrasial conditions of the plasma, occurs under several forms, some of which have been already adverted to, especially those of turgescence, pallor, or pre-ternaturally deep coloration; of augmented or diminished adhesiveness; and the like. As an independent anomaly, their diminished number in genuine chlorosis is alone recognized.
Oilier erases deserving of notice are:
The hemorrhagic crasis [haemorrophilis], specified in the chapter on "Hemorrhage".
A crasis which determines the deposition or stratiform coagulation of a protein substance upon the inner coat of bloodvessels cannot, in our opinion, be pretermitted. The little that we have to advance upon this subject, however, we shall reserve for the chapter on "Diseases of the Arteries," in vol. iii.
The retention of urea in the blood occasions and sustains a hypinotic crasis; and in certain cases, as in acute nephritis and acute albuminuria, tends to induce a complete decomposition of the blood.
A biliary dyscrasis is produced in two different ways: first, through diseases of the liver and gall-ducts, - inflammation of the liver, obstruction of the latter through retention in the blood of the elements of the bile; and secondly, through endosmosis of bile (resorption) into the bloodvessels.
The croupous-crasis and pyaemia often give rise, without demonstrable liver affection, to the elements of the bile being set at large in the blood.
In fine, there is a spontaneous biliary crasis which, running a very acute course under the most intense typhoid symptoms, and under colli-quation of the parenchyma of the liver, proves fatal through decomposition of the blood. So intense and violent is the conversion to bile in the blood, that even in the portal circulation, previous to its entrance into the liver, the blood has the look of blood impaired by artificial contact with bile. It is a dingy-brown or yellow-red, tenacious, ichorous-looking fluid intermingled with whitish fat-streaks and jelly-like particles of fibrin. The bile secreted in the liver is so saturated, and at the same time so excessive in quantity, as to utterly dissolve the parenchyma of that organ, - that is, the hepatic cells - determining a state of collapse and softening, which, in its appropriate place, we shall treat of as "Acute Yellow Atrophy of the Liver".
With regard to the constitution of the blood in gout, syphilis, chronic skin eruptions, and many other diseases, although in each a particular anomaly does no doubt exist, it has not as yet been given to morbid anatomy to substantiate its nature.
 
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