This section is from the book "A Manual Of Pathological Anatomy", by Carl Rokitansky, William Edward Swaine. Also available from Amazon: A Manual of Pathological Anatomy.
Typhus associates itself with tuberculosis only under the influence of very intense epidemics; in other words, it very seldom attacks tuberculous individuals. On the other hand, a fibrino-croupous tubercle-crasis developes itself not unfrequently in the sequel to typhus, and with it local inflammation with fibrino-croupous exudation of a tuberculous nature. This occurs in the shape of inflammations of the lungs, and also of such follicles of the ileum as have escaped the typhous process. This determines, from the softening of the tubercle around the typhous loss of substance, a combination of the so-called typhous with the tuberculous intestinal ulcer.
This tuberculosis in the sequel to typhus is without doubt based upon the not unfrequent conversion of the typhous to the fibrino-croupous crasis. The conversion takes place at different periods, but frequently at a very early stage of the retrogressive typhous process.
There is a similar relation of tuberculosis to the acute exanthemata; especially to scarlatina and measles. The tuberculosis following them is, for the most part, fibrino-croupous, and dependent upon a similar conversion of the exanthematous crasis.
The experience of foreigners places their incompatibility with each other beyond any doubt.
Although within the range of our own observation a moderate degree of sporadic goitre has not seemed necessarily to possess an exclusive relation towards tubercle, the observations of foreigners as to the exclusive relation of endemic goitre to tuberculosis merit, nevertheless, to be noticed here. Apart from the affinity in the structural relations of the enlarged thyroid gland, goitre presents, in the outpouring of colloid, important points of analogy with cysts, sarcomata, and cancers, in which colloid often constitutes an essential ingredient. It would seem that, in endemic goitre, it is not the mechanical hinderance to respiration that occasions consecutively, but an anomaly of the crasis connected with the secretion of colloid in the thyroid gland, that determines primitively the exclusion of tuberculosis. (See Colloid.) This is betokened by the alienation of the general habit contracted with goitre, and still more by the fact that, in districts where goitre is endemic, tuberculosis does not occur, even in individuals unaffected with the prevailing deformity.
Rickets And Tuberculosis do not readily combine. Nay, rachitic deformity and coarctation of the thorax are scarcely ever found complicated with tuberculosis. It is, as yet, undecided whether, or what degree of, exclusiveness towards tubercle absolutely belongs to rickets; and, again, whether the latter owe not its immunity to a consecutive disproportion of its own creation, namely, the deformity - the narrowing - of the thorax.
Even the arterial disease upon which spontaneous aneurism depends, and which consists in the endogenous exudation and stratification of a fibrinous substance upon the internal bloodvessel membrane (see Abnormal Conditions of the Arteries) is, in its more highly developed grades, very rarely associated with tuberculosis. The immunity is, perhaps, based upon an exhaustion of the materials for tubercle, due to the deposition of a solidifying blastema out of arterial blood. A more decided immunity is brought about by aneurisms, or by a single extensive aneurism, in the proximity of the heart, involving the endogenous coagulation of great fibrinous masses, and a consequent hydremia through defibrination of the blood.
 
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