The so-called issues of inflammation comprehend a variety of processes. They concern either the inflammation itself or its products and the involved structures; that is to say, they embrace, in the latter relation, the changes which both the inflammatory products and the textures themselves undergo.

To the former category belong:

1. Resolution or dispersion of the inflammation. To the second belong:

2. Reliquefaction and resorption of the inflammatory products.

3. Abiding of the inflammatory products in various forms, including, amongst others, the issue in induration, and in inflammatory hypertrophy.

4. Suppuration, ichorous, ulcerous destruction of textures.

We cannot ourselves regard suppuration as an issue of inflammation. Wherefore we have treated of pus and ichor as of products of inflammation, under the head of "exudates".

Of the issue of inflammation in gangrene, of so-called inflammatory gangrene, we cannot well treat separately. We therefore refer the consideration of this point to a subsequent chapter, to be devoted to the subject of gangrene.

1. Resolution Of The Inflammation

Issue in resolution relates directly to the inflammatory process. It consists in a cessation of the latter, previously to any act of effusion; that is, in a reduction of the existing stasis.

As determining conditions, we may adduce:

(a.) Cessation of the efficient cause of inflammation; and, as a consequence, cessation of the palsy of the bloodvessels, and returning contractility of the latter.

(6.) Reinforced impulse from the arteries, brought about by the said contractility of the capillaries, one effect of which is a return of the phenomenon of oscillating motion in the arrested blood-column.

(c.) Liberation of the blood-corpuscles from a state of mutual cohesion, through endosmosis of the exuded blood-serum into the vessels charged with concentrated plasma. The blood-corpuscles lose the flattened condition and deep color which they had acquired in the stasis, swell out, and become spherical and at the same time paler.

(d.) The uninterrupted circulation in the capillaries surrounding an inflammation, plays its part likewise, portions of the stagnant blood-column being (according to Emmert) forcibly separated by the laving current, and a passage forced here and there through an entire capillary range.

Obstacles sometimes present themselves to the resolution of inflammation; and even when the process is accomplished, certain residua are left behind:

(1.) The blood-corpuscles are so firmly wedged in the dilated capillaries, as to resist both the contraction of the latter and the increased impulse from the arteries. This occasions a protracted stasis of a mechanical nature.

(2.) Even after removal of the stasis, a certain degree of palsy and dilatation of the capillaries may remain entailed. The part previously inflamed continues in a state of hyperaemia, and prone to relapse into inflammation. This tendency increases greatly upon repetition. The resolution of local inflammations dependent on external causes, is common only where these causes are slight.

Inflammations dependent upon internal dyscrasial influences rarely terminate thus. An essential condition of their so doing is the extinction of the dyscrasis. If without this the inflammation take such an issue, it will localize itself in other organs standing in the relation of sympathy with that originally affected.

Even this favorable consummation of the inflammatory act is not a matter of indifference for the organism, seeing that plasma, altered by the previous stasis, is copiously received back again into the blood. The consequences are obvious, and directly commensurate with the extent of the inflammation.