These are not of common occurrence apart from tuberculosis and syphilis. Amyloid disease is the commonest form of degeneration, but it does not usually occur in a high degree, and it is only occasionally that the glands are enlarged and rendered firmer by the degeneration. For the most part it is detected only when the glands are examined microscopically with the aid of iodine or methyl-violet. The disease appears to attack mainly the reticulum of the gland, and one can sometimes make out the swollen hyaline network, or even detect how the normal reticulum swells out into the degenerated network. In old persons a Colloid or Hyaline degeneration is met with. The gland shows a series of alveoli filled with colloid material, or the blood-vessels and trabecular of the gland become hyaline, the appearance resembling that in amyloid disease but without the reaction.